All Vaccinology articles
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World-first koala chlamydia vaccine approved
In a world first, a vaccine has been approved to protect Australia’s endangered koalas from infection and death caused by chlamydia.
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Study reveals how dengue rewires the immune system, reshaping vaccine response
Just as a computer’s operating system can be rewritten after a major update, dengue infection can ‘re-programme’ the body’s immune system, leaving a long-lasting genetic imprint that influences how people respond to future infections—an effect not seen with vaccination.
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Protein discovery gives new hope for longer COVID protection
Scientists have discovered that the body’s immune system strongly reacts to an internal protein from SARS-CoV-2, the virus that causes COVID-19, which mutates less frequently than the surface-spike protein currently targeted by vaccines.
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Study suggests link between hepatitis B immunity and lower risk of developing diabetes
A research study shows that overall HBV immunity is linked with a 15% lower risk of diabetes, with higher protection in younger people and those with higher immunity shown by higher antibody levels.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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Pertussis resurgence in Tuscany outlines importance of timely vaccination in Italy
Research analysing 2016-2024 data from all pertussis-related hospitalisations in Tuscany, Italy, finds a ninefold increase in pertussis cases in 2024 among children and adolescents.
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Seroprevalence 36 months after a single-dose bivalent HPV vaccination among nine to fifteen-year-old girls
A single-dose bivalent HPV vaccine induces sustained immunity in Bangladeshi adolescent girls, with lower HPV16 seropositivity among older girls and those in higher grades, with higher HPV18 seropositivity linked to lower household income.
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New African swine fever vaccine candidate shows promise against some virus strains
An international team of scientists has found that a promising African swine fever (ASF) vaccine can protect pigs against some strains of the virus but offers little or no protection against others.
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1 in 3 US adults unaware of connection between HPV and cancers
The human papillomavirus (HPV) can cause six types of cancer, yet new analysis shows that most people are unaware of the connection between HPV and all of these cancers.
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Broad COVID-19 vaccination makes economic sense, especially for older adults, study finds
Vaccinating every person over 65 would actually save the U.S. money, while vaccinating all younger adults would be a reasonable investment, according to a new study.
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Study: Long COVID remains a substantial financial and medical burden
Individuals with long COVID-19 experienced worse financial and employment outcomes – lasting up to three years after their initial infection. Notably, vaccination against COVID-19 was associated with strikingly improved work and financial outcomes.
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Global Virus Network reaffirms support for mRNA vaccines and collaborative vaccine research
The Global Virus Network (GVN) has announced that it is unequivocally committed to the continued development and deployment of mRNA vaccines and the global scientific collaboration that makes such innovation possible.
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Malaria vaccine mimics natural immunity with high precision
A detailed analysis reveals one of the reasons why the R21/Matrix-M malaria vaccine works so well: the antibodies generated following vaccination are indistinguishable from those found in people who have been infected by the parasites.
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Scientists develop new approach to fighting many viruses at once
Scientists have developed a research pipeline to fuel the development of “universal vaccines,” that would address broad viral families and mutated viral variants.
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National study urges expanded vaccine screening in emergency departments
About 49% of people are unaware of one or more vaccines recommended for them. Further, 86% have not received one or more of these vaccines, according to the first national comprehensive vaccine surveillance study conducted in emergency departments.
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Revealed: New vaccine target to block malaria transmission
Researchers have visualised a key protein complex in malaria parasites for the first time, uncovering a new target for next-generation vaccines that could help stop the disease from spreading.
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Nanoparticles that self-assemble at room temperature could transform vaccine delivery
Researchers have engineered polymer-based nanoparticles that form with a simple temperature shift—no harsh chemicals, no specialized equipment, and no processing needed. They can self-assemble at room temperature and deliver RNA to living cells.
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New farmer-led research project explores how badger vaccination may be used within TB eradication strategy
A progressive new UK project is underway to explore the contribution, effectiveness and practicality of professionally scaled-up, industry delivered badger vaccination as part of a comprehensive TB eradication strategy.
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Study highlights the severity of acute necrotizing encephalopathy in kids with the flu
For a small subset of children, influenza can trigger a rare but serious complication called influenza-associated acute necrotizing encephalopathy (ANE). Now, findings of a multicenter study suggest that ANE is often fatal in these children — despite intensive treatment.
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Mucosal vaccine shows transient action against Covid-19 variant
Mucosal adenovirus vaccine Ad5-XBB.1.5 boosting elicits nasal IgA and transiently prevents JN.1 wave infection for less than 6 months in real-world settings, a new study reveals.