All Viruses articles – Page 16
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Scientists culture previously uncultivable human rhinovirus C with innovative respiratory organoids
Scientists have successfully utilised human respiratory organoids (mini-organs) established by their team to propagate human rhinovirus C (HRV-C), which had previously been refractory to conventional virus cultivation.
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Towards improved pandemic preparedness: Launch of new EU project COMBINE
A project for the targeted development of antiviral therapies for newly emerging viruses, COMBINE focuses on the critical virus-cell binding step, aiming to identify key factors and potential therapeutic targets involved early in viral infections.
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Dihydroartemisinin inhibits T cell activation in people living with HIV with incomplete immune reconstitution in vitro
A new study provides insights into the biological mechanisms underlying incomplete immune reconstitution in people with HIV and supports dihydroartemisinin’s potential as a therapeutic agent.
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Human papillomavirus infection kinetics revealed in new longitudinal study
Non-persistent human papillomavirus (HPV) infections are characterized by a sharp increase in viral load followed by a long plateau, according to a new study.
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A Marburg virus outbreak was confirmed in Tanzania
WHO has announced that an outbreak of Marburg virus disease in Tanzania has been confirmed, with 25 suspected cases. Outbreak control measures have been established since the announcement.
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Scientists uncover structure of critical component in deadly Nipah virus
Through the structural and functional study of the deadly Nipah virus, a research team has identified a crucial viral component, viral polymerase complex, within its multiplication machinery, with which a part of the enzyme could potentially serve as a therapeutic target.
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WHO calls on Trump to reconsider order that USA will withdraw from the Organization
The World Health Organization has said it regrets President Donald Trump’s announcement that the United States of America intends to withdraw from the Organization.
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Ancient viral DNA shapes early embryo development
Over half of our genomes consists of remnants of ancient viral DNA which are widespread across the tree of life. Once dismissed as the ’dark side’ of the genome, researchers have now revealed the role of transposable elements in early embryo development.
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Valneva reports high sustained immune response in adolescents one year after Chikungunya Vaccine
Valneva SE, a specialty vaccine company, has reported further positive Phase 3 data in adolescents for its single-shot chikungunya virus (CHIKV) vaccine, IXCHIQ®, which showed a sustained 98.3% sero-response rate one-year after single vaccination.
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Research team receives $1.5 million to study neurological disorders linked to long COVID
A significant grant was awarded for an upcoming research of cellular and molecular mechanisms in the neurological challenges posed by long COVID-19.
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Tiny vortices help detect dangerous viruses
Due to the specific wavelengths of vibrations used to create these tiny whirlpools, they efficiently trap cells, bacteria and other larger bioparticles found in saliva while leaving antibodies and viruses free to flow forward through multiple biosensing chambers.
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Decoding HIV genomic tactics in viral replication
Research on HIV-1 unravels the viral and host translational regulations during viral replications through the identification of RNA structures and previously unrecognized genetic elements - this could bring potential therapeutic interventions to counter the viral manipulations.
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Rotavirus protein NSP4 manipulates gastrointestinal disease severity
This study is among the first to show that the rotavirus protein NSP4 is both necessary and sufficient for multiple aspects of rotavirus infection by disrupting calcium signaling not only within infected cells but also in nearby uninfected cells.
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Effectiveness and safety of tenofovir amibufenamide in the treatment of chronic hepatitis B: A real-world, multicenter study
A new study aimed to evaluate the real-world effectiveness and safety of tenofovir amibufenamide (TMF) in a cohort of patients with chronic hepatitis B (CHB).
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Uprooting Cassava Disease: scientists identify causes of two devastating diseases
In a series of studies, researchers have established the pathogens and the first diagnostic tests for two diseases: Cassava Frogskin Disease and Cassava Witches’ Broom Disease.
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Child undernutrition may be contributing to global measles outbreaks
A study of fully vaccinated children finds a link between stunted growth and weakened immunity, suggesting combatting child hunger could help prevent the disease’s spread.
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Chain reaction: HIV vaccines can lead to antibodies against antibodies
Scientists have discovered that repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus—knowledge that could lead to better vaccines.
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The hunt narrows for Ebola virus hosts
A cholesterol-trafficking receptor, Niemann-Pick C1 (NPC1), was identified for more efficient surveillance of host reservoirs of filoviruses, including Ebolaviruses. It narrows down the host species of the virus and links to the geographic information of pathogen emergence.
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Scientists develop new 'twindemic' diagnostic system for rapid viral testing
A team of scientists has recently developed a novel TwinDemic Detection (TDD) system, designed for simultaneous detection of SARS-CoV and influenza A virus (IAV).
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Bird flu is mutating - but antivirals still work
Researchers have identified nine mutations in a bird flu strain from a person in Texas. The bad news: this strain is more capable of causing disease and replicates better in the brain. Good news: approved antivirals are still effective.