All Clinical & Diagnostics articles – Page 10
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AI enables faster, more effective antibiotic treatment of sepsis
Sepsis is a life-threatening infection complication and accounts for 1.7 million hospitalizations and 350,000 deaths annually in the U.S. Fast and accurate diagnosis is critical, as mortality risk increases up to 8% every hour without effective treatment. Source: Ilanaer42 However, the current diagnostic standard is reliant on ...
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Living bioelectronics combine sensors and bacteria to heal skin
Researchers have created a unique prototype of a ‘living bioelectronic’ designed to treat psoriasis. The patch – a combination of advanced electronics, living cells and hydrogel – is showing efficacy in experiments in mice.
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New HIV reporter model: Visualizing HIV viral dynamics in cells with dual fluorescence
Researchers have developed a novel viral reporter system that allows for real-time visualization of HIV dynamics post-viral infection. HIV-Tocky features dual fluorescence to illuminate the process of provirus silencing and reactivation.
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Ingestible microbiome sampling pill technology takes a step forward
Significant progress has been made in the development of a small device, about the size of a vitamin pill, that can be swallowed and passed through the gastrointestinal tract to sample the full inventory of microorganisms.
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Precision medicine for sepsis in children within reach
Researchers used artificial intelligence to analyze a large set of clinical data and find a distinct group of patients who might respond better to targeted sepsis treatments.
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Oral nucleoside antiviral is progressing toward future pandemic preparedness
Oral obeldesivir has been shown to reduce disease severity in mice infected with one of several different coronaviruses, including SARS-CoV-2 (which causes COVID-19), SARS-CoV and MERS-CoV.
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Novel triple antibiotic combination offers breakthrough in combatting antibiotic resistance
A new study unveils a promising triple combination of antibiotics that significantly expands our arsenal against drug-resistant bacteria.
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Statisticians call for rigour and transparency in the evaluation of diagnostic tests
Recommendations designed to reframe the evaluation of in vitro diagnostic tests have been published - intended to help prevent future scenarios in which IVDs are marketed widely, but later attract serious concerns about the standards applied to their evaluation.
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Human cervix modeled in microfluidic organ chip helps target bacterial vaginosis
Engineered cervix with in vivo-like mucus production, hormone sensitivity, and associated microbiome creates novel testbed for bacterial vaginosis therapeutics and other treatments.
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New electrostatic sampler boosts indoor virus detection speed
Researchers have developed a groundbreaking electrostatic air sampler that enhances the rapid monitoring of airborne influenza and coronavirus.
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Living bioelectronic device monitors and manages psoriasis in mice
Coupling skin bacteria-laden hydrogel and electronics, researchers have introduced a bioelectronics system that can deliver management and adaptive treatment of skin inflammation. They test this approach in a mouse model of psoriasis.
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Lung microbiomes predict mortality in children following bone marrow transplant
Using a method that identifies all potentially pathogenic organisms present in the lungs, scientists have discovered links between certain microbial communities and the relative risk of mortality in children who undergo bone marrow transplants.
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Specific microbial hallmarks in vagina could indicate gynecological cancers
A new study demonstrates unique vaginal microbiome in patients with gynecological cancers which could function as a biomarker.
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New test rapidly diagnoses cat parasite infections and reduces false positives
An easy-to-use test and new paradigm for care can help save lives, sight, cognition and motor function by rapidly diagnosing and treating Toxoplasma infections.
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Biotech companies leverage novel tools to develop drugs for RSV
Reporter structures that can be introduced into cells for use in drug screening assays emit fluorescent or bioluminescent light at different intensities when RSV genes are inhibited by the potential antiviral agents being tested.
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New tool may help prioritize high-risk infants for RSV immunization
On the heels of a shortage of nirsevimab for infant respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) prevention, a new tool may help identify newborns at highest risk for developing serious infections.
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Biophysicist F. William Studier awarded Merkin prize in biomedical technology
F. William Studier, a senior biophysicist emeritus at the U.S. Department of Energy’s (DOE) Brookhaven National Laboratory, has won the 2024 Richard N. Merkin Prize in Biomedical Technology for his development in the 1980s of an efficient, scalable method of producing RNA and proteins in the laboratory. Source: ...
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Astragalus polysaccharide enhances voriconazole metabolism under inflammatory conditions through the gut microbiota
Astragalus polysaccharide alleviates the reduction of VRC metabolism induced by LPS by inhibiting lipid accumulation and inflammatory cytokine levels in the serum and liver and improving the metabolic function of the liver, a new study shows.
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Scientists reveal search for faster way to diagnose MRSA and its relatives
New research being presented at the Letters in Applied Microbiology ECS Symposium reveals the drive to come up with a better way of diagnosing staph infections that would be more cost-effective and less time-consuming.
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Diagnostic assay could identify AMR infections within hours
New research being presented at the Letters in Applied Microbiology ECS Symposium this May reveals how a new assay could potentially diagnose antimicrobial resistant infections within a matter of hours.