All Clinical & Diagnostics articles – Page 10
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CareersSummer studentship: Oliver probes AMR in neonatal sepsis - and use of novel bacterial screening methods.
Oliver Spiller-Boulter, from Cardiff, reports back on his AMI-sponsored summer studentship which examined antimicrobial resistance (AMR) in neonatal sepsis and the use of novel bacterial screening methods.
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NewsCorticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and acute respiratory distress syndrome and may reduce secondary shock in severe pneumonia.
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NewsLong-term HIV control: Could this combination therapy be the key?
A new study shows it may be possible to control HIV without long-term antiviral treatment — an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.
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NewsNew prevention tools and investment in services essential in the fight against AIDS
On World AIDS Day, the World Health Organization (WHO) calls on governments and partners to rapidly expand access to new WHO-approved tools including lenacapavir (LEN) to drive down infections and counter disruption to essential health services caused by cuts to foreign aid.
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NewsNew guideline on pre-exposure and postexposure HIV prevention
Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these options to patients.
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NewsBird flu viruses are resistant to fever, making them a major threat to humans
Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body’s ways of stopping viruses in their tracks, according to new research.
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NewsFractional-dose vaccines can save millions during shortages
New research shows that using smaller, fractional doses of vaccines can significantly reduce infections during epidemics, especially when vaccine supply, delivery, or administration capacity is limited.
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NewsExperimental mRNA therapy shows potential to combat antibiotic-resistant infections
Researchers have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria. In preclinical studies, the therapy slowed bacterial growth, strengthened immune cell activity, and reduced lung tissue damage in models of multidrug-resistant pneumonia.
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NewsHospital bug jumps from lungs to gut, raising sepsis risk
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.
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NewsRebalancing lung repair with immune damage is key to surviving severe influenza
Recovery from deadly influenza infection may hinge on helping the lungs heal in addition to stopping the virus, according to a new study in mice, which shows that pairing modest antiviral therapies with immune modulation can restore damaged tissues and lung function, even after severe infection has taken hold.
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NewsMaternal health programme cuts infection deaths by 32%
A landmark multi-country clinical trial has shown that a structured, sustainable approach to infection prevention and treatment can save women’s lives, cutting severe maternal infections and deaths by about one-third (32%) compared to usual care.
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NewsResearchers diagnose disease with a drop of blood, a microscope and AI
Scientists have developed an automated, high-throughput system that relies on imaging droplets of biofluids for disease diagnosis in an attempt to reduce the number of consumables and equipment needed for biomedical testing.
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NewsScientists use computer model to improve hospitals’ ability to limit spread of drug-resistant infections
The computer model improves on traditional methods like contact tracing by inferring asymptomatic carriers in the spread of antibiotic-resistant infections.
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NewsBacteria ‘pills’ could detect gut diseases — without the endoscope
Researchers report that they’ve developed a sensor made of tiny microspheres packed with blood-sensing bacteria that detect markers of gastrointestinal disease. Taken orally, the miniature “pills” also contain magnetic particles that make them easy to collect from stool. Excreted from mouse models with colitis, the bacterial sensor detected gastrointestinal bleeding within minutes.
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NewsPhase 2 clinical trial results show potential to shorten TB treatment time
New clinical trial results show that the novel antibiotic candidate sorfequiline (TBAJ-876), a next-generation diarylquinoline, has the potential to improve tuberculosis (TB) treatment when combined with pretomanid and linezolid in a treatment regimen known as “SPaL.”
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NewsBiomedical Sciences researcher receives nearly $7 million in federal grants to fight STIs
Cynthia Nau Cornelissen, a Distinguished University Professor and associate director of the Institute for Biomedical Sciences at Georgia State University, has received nearly $7 million in two, five-year federal grants to develop vaccines and therapeutics to combat sexually transmitted infections (STIs).
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NewsExperts urge continued hepatitis B vaccine birth doses for newborns
In a new commentary, leading experts urge that all newborns in the United States continue to receive the first dose of hepatitis B vaccine within 24 hours of birth. Hepatitis B vaccines are safe and effective with over one billion doses administered worldwide.
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NewsNew test could allow for more accurate Lyme disease diagnosis
Researchers have developed a new way to detect the Lyme disease bacterium Borrelia burgdorferi, allowing for faster and more accurate diagnosis.
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NewsNew test could speed detection of three serious regional fungal infections
Researchers have developed a new molecular test capable of detecting three major pathogenic fungi at once — and with a much quicker turnaround than traditional methods.
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NewsTyphoid conjugate vaccine demonstrates strong safety and immunogenicity: Results from Phase 3 study
PATH and EuBiologics Co., LTD have announced Phase 3 results from a clinical trial of a typhoid conjugate vaccine (TCV), EuTYPH-C Inj.® Multi-dose. EuTYPH-C Inj.® Source: CDC/ Armed Forces Institute of Pathology, Charles N. Farmer This photomicrograph reveals some of the histopathology exhibited in a lymph node tissue ...