All Clinical & Diagnostics articles – Page 9
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NewsSunlight-activated nanospray enables painless, antibiotic-free therapy for infected diabetic wounds
A research team has reported a multifunctional photodynamic nanospray for chronic infected wounds that harnesses natural sunlight to address persistent bacterial infections, impaired healing and severe pain simultaneously.
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NewsResearcher reveals secrets of bacteria that can swim upstream
Rather than washing pathogens away, strong fluid currents act as “guide rails” that align bacteria and accelerate their upstream migration. They discovered that this creates a “two-way invasion” where pioneer cells reach the source within minutes, seeding colonies that spread threefold faster than in still water.
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NewsNew biosensor technology could transform how viruses are detected
A new review highlights major advances in a promising class of diagnostic tools known as aptamer-based biosensors, which could help deliver faster, cheaper, and more portable virus testing in clinics, communities, and the field.
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NewsBeyond gene scissors: New CRISPR mechanism discovered
Two studies describe how researchers found a novel CRISPR mechanism, Cas12a2, in a family of nucleases that exclusively cleave DNA. In contrast, Cas12a2 was able to broadly cleave both RNA and DNA.
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NewsCRISPR discovery could lead to single diagnostic test for COVID, flu, RSV
Researchers report newly discovered details about the Cas12a3 immune system that precisely targets transfer RNA in invading pathogens, without destroying host cells.
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NewsNew clinical standards strengthen antimicrobial stewardship in tuberculosis care
An international panel of experts from 32 countries has presented specific antimicrobial stewardship standards for TB care for the first time.
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NewsHigh-dose antibiotic does not reduce mortality in tuberculous meningitis
The first trial examining the effects of higher rifampicin doses on tuberculosis survival has been completed. The study found no evidence of a beneficial effect from high-dose rifampicin.
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NewsFiltering the invisible: New evidence points to more efficient indoor air microbe sampling
Using fluorescence-based detection, a new study provides clear, quantitative evidence that sampling principle, collection medium, and airflow rate strongly shape how well indoor microbial aerosols can be measured.
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NewsScientists identify potential therapy and diagnostic markers for cerebral malaria
Researchers examined whether methylene blue could mitigate brain injury during severe malaria, and whether a practical set of blood biomarkers could help clinicians identify cerebral malaria early and track how patients respond to treatment.
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NewsA ‘one-pot’ assay of or rapid portable identification of genotypes I and II African swine fever viruses
Researchers in search of an African swine fever virus genotyping method developed an isothermal ‘one-pot’ CRISPR-Cas12i3/Cas13d-based assay, designated OBServe.v2, to detect two amplified targets from multiplex recombinase polymerase amplification (RPA) in a single tube.
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NewsCan an electronic nose detect indoor mold?
Researchers have developed an electronic nose that can reliably sense and identify mold, which causes various health issues for humans and animals, as well as damage to homes and other buildings and structures.
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NewsNew method accelerates resistance testing in urinary tract infections
Researchers have developed two methods that allow urine samples to be tested directly for antibiotic susceptibility. Because the procedures do not require standardized bacterial suspensions, the time to result is reduced by up to 24 hours compared to conventional testing.
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NewsWho is more likely to get long COVID?
Scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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NewsNew 15-minute hepatitis C test paves the way for same-day treatment
Scientists have developed the fastest test yet for diagnosing hepatitis C virus (HCV). The highly accurate diagnostic delivers results to patients in just 15 minutes - crucial for kickstarting patients’ treatment before they leave their appointment.
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NewsCARB-X to support investigation of Exhalon’s breath-based lower respiratory tract infection testing platform
CARB-X has awarded Exhalon US$1M in seed funding to evaluate whether exhaled breath can be used as a non-invasive sample type to aid in the rapid and accurate diagnosis of lower-respiratory tract infections (LRTIs).
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NewsInside the gut: What our poo could tell us about our diet, gut microbes and health
Researchers have found that molecules in stool samples can accurately reflect what people eat and how their gut microbiome responds, offering a potential new tool to study nutrition and its impact on health.
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NewsSingle-cell movies reveal how host physiology sets phage success - and how to time therapies
A new study outlines how an innovative imaging platform can be used to help uncover the reasons why phages succeed or fail when used to target bacterial infections.
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NewsNew test distinguishes vaccine-induced false positives from active HIV infection
A new device correctly identified those with active HIV-1 infection 95% of the time and those without active infection but with vaccine-induced molecules that could trigger a false positive, 98% of the time.
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NewsBridging controversy: New international guidelines redefine diagnosis and treatment of fungal eye infections
A global expert panel from the Asia-Pacific region has now issued 20 consensus statements providing comprehensive, evidence-based guidance for the diagnosis and management of a sight-threatening condition - fungal endophthalmitis.
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NewsPoint-of-care rapid tests can improve screening for latent tuberculosis
A new test shows promising results for detecting latent tuberculosis infection in resource-limited settings. Latent tuberculosis is often diagnosed using a laboratory test called QuantiFERON-TB Gold Plus - this was compared with another test, TB-Feron.