All Clinical & Diagnostics articles – Page 4
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News
Regional differences in antibiotic use in newborns
There are relatively large regional differences in Sweden in the proportion of newborns receiving antibiotics for suspected sepsis, according to a study. The researchers want to call attention to overuse as well as highlight good examples.
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Researchers debunk long-standing concern about flu treatment in children
Researchers have debunked a long-standing theory about oseltamivir, known as Tamiflu. Oseltamivir treatment during flu episodes was associated with a reduced risk of serious neuropsychiatric events, such as seizures, altered mental status and hallucination.
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Skin test reagent proves effective and safe for TB diagnosis in children
A new class of skin test reagents based on Mycobacterium tuberculosis (MTB)-specific antigens has been developed. A phase III clinical trial suggests that C-TST is an effective and safe option for diagnosing pediatric TBI.
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Scientists pinpoint optimal dose of methylprednisolone for treating severe Mycoplasma pneumoniae pneumonia
Investigators have compared the efficacy of low- versus high-dose of methylprednisolone in preventing pulmonary lesions in children with severe Mycoplasma pneumoniae pneumonia.
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A non-invasive test enables accurate detection of infant meningitis
A high-resolution ultrasound device has shown great accuracy in detecting suspected meningitis in newborns and infants, potentially offering a non-invasive alternative to lumbar puncture, the traditional diagnostic method.
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AI poised to revolutionize Lyme disease testing and treatment
Researchers unveiled a blood test developed with the help of artificial intelligence (AI) that identifies Lyme disease sooner and more accurately than the current standard — and that could translate to vastly improved patient outcomes.
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New study in Ukraine indicates significant lifetime exposure and ongoing transmission of hepatitis B and C viruses among the general population
A nationwide study in Ukraine has found evidence of significant exposure to hepatitis B and C viruses and substantial ongoing circulation among the population, highlighting need for immunisation and regular screening.
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How AI can enhance early detection of emerging viruses: study
Coupling wastewater surveillance and a newly developed AI algorithm can help public health organizations more quickly predict potential outbreaks, a new study suggests.
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Study uncovers the hidden emerging pathogen behind Aspergillosis cases in Japan
Scientists have discovered the ancestral evolutionary links of Aspergillus latus strains through in-depth genome sequencing analyses.
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Tumor-targeting fluorescent bacteria illuminate cancer for precision surgery
Researchers have developed a next-generation intraoperative imaging platform using engineered beneficial bacteria that emit fluorescence specifically at tumor sites. This illuminates tumors like a neon sign during surgery, enabling more precise resection and reducing risk of recurrence.
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New insights into malaria: Proteins in the blood can reveal the severity of the disease
Researchers have identified over 250 proteins that are strongly affected by malaria, which could help predict the severity of the disease and thus enable faster treatment for the most critical patients.
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Novel open-source diagnostic tool offers affordable, reliable pathogen detection for resource-limited settings
Researchers have developed an open-source reverse transcription loop-mediated isothermal amplification (RT-LAMP) assay that is lyophilized for heat stability and uses non-proprietary components, making it an affordable tool for pathogen detection in diverse settings.
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From COVID to cancer, new at-home ‘coffee-ring’ test spots disease with startling accuracy
A new, low-cost biosensing technology could make rapid at-home tests up to 100 times more sensitive to viruses like COVID-19. The diagnostic could expand rapid screening to other life-threatening conditions like prostate cancer and sepsis as well.
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Scientists investigate gut microbiota in elderly patients with acute hepatitis E infection
A new study of the impact of hepatitis E virus infection on the gut microbiota identifies a bacterial species as a potential biomarker for disease outcomes.
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Researchers develop AI tool to detect surgical site infections from patient-submitted photos
Researchers have developed an artificial intelligence (AI) system that can detect surgical site infections (SSIs) with high accuracy from patient-submitted postoperative wound photos, potentially transforming how postoperative care is delivered.
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Engineers develop electrochemical sensors for cheap, disposable diagnostics
Electrodes coated with DNA could enable inexpensive tests with a long shelf-life, which could detect many diseases and be deployed in the doctor’s office or at home.
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Features
Tap water troubles: how drinking water systems contribute to NTM infections
Commonly found in dust and soil, NTM are worrying microbiologists and health experts alike. But is tap water an unsuspected vehicle for these deceptively harmful infections?
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Antibiotics are failing in many countries in Africa, new study reveals
The largest retrospective study on resistance to antibiotics in Africa highlights the need for major investments to enhance laboratory capabilities and healthcare access.
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New test could save lives from deadly fungal infection that spiked during pandemic
A new lateral-flow test could one day save lives across the world through early detection of a deadly fungal disease which dramatically spiked during the COVID-19 pandemic.
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New RNA test for African trypanosomiasis in livestock aids control efforts
A new state-of-the-art diagnostic test for animal African trypanosomiasis could detect sentinels of infection in domestic animals and aid control efforts.