All Clinical & Diagnostics articles – Page 4
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NewsAdverse event profiles following HPV vaccination in males
The safety profile among male recipients of human papillomavirus (HPV) vaccination remains a critical evidence gap. A new study presents the first systematic safety evaluation of Gardasil 9 and Gardasil in male recipients.
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NewsHPV integration: Moving from carcinogenesis mechanisms to clinical applications
The clinical significance of HPV integration into the host genome is substantial, particularly in cervical cancer screening programs. Integration testing has emerged as a valuable triage tool for detecting high-grade cervical intraepithelial neoplasia (CIN III+).
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NewsNew CRISPR test could make tuberculosis screening as simple as a mouth swab
Researchers have developed an enhanced CRISPR-based tuberculosis test that works with a simple tongue swab, a potential breakthrough that could allow easier, community-based screenings for the world’s deadliest infectious disease.
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NewsBout of cystitis may signal presence of urogenital cancers in middle-aged adults
A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle aged adults, suggests research. The risks seem to be especially high within 3 months of infection.
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NewsMedications leave lasting mark on the gut microbiome, even years after use
Analysing stool samples and prescription records from over 2,500 Estonian Biobank participants, researchers found that the majority of drugs studied were linked to microbiome changes, with a substantial number of them also showing long-term effects detectable years after patients stopped taking them.
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NewsMicrobial allies: Bacteria help fight against cancer
An international team of scientists have discovered that microbes associated with tumours produce a molecule that can control cancer progression and boost the effectiveness of chemotherapy.
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NewsPediatric investigation study re-examines chikungunya in neglected pediatric victims
Researchers and policymakers must recalibrate their outlook on pediatric chikungunya to develop effective control measures, a new paper warns.
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NewsResearcher developing electronic nose to detect foodborne illness
A researcher is working on developing an electronic nose (e-nose) to detect abnormalities from their version of the sniff test. The method would revolutionize food safety by relying on what the e-nose can detect rather than only the appearance of the food.
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NewsBlood test identifies HPV-associated head and neck cancers up to 10 years before symptoms
Researchers show that a novel liquid biopsy tool called HPV-DeepSeek can identify HPV-associated head and neck cancer up to 10 years before symptoms appear.
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NewsEven healthy children can be severely affected by RSV
It is not only premature babies and children with underlying diseases who suffer from serious respiratory syncytial virus (RSV) infections. Even healthy, full-term babies are at significant risk of intensive care or prolonged hospitalisation – especially during the first three months of life.
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NewsCoral-inspired pill offers a new window into the hidden world of the gut
Marine corals have evolved intricate, porous structures that shelter diverse microbial communities. Researchers have borrowed this biological blueprint to create an ingestible pill that can sample bacteria from one of the most inaccessible regions of the human body: the small intestine.
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NewsFrailty fuels gut imbalance and post-surgery gastrointestinal risks
Scientists found that residual intra-abdominal microbes, especially in frail patients, drive gastrointestinal complications after bladder cancer surgery.
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NewsDe-mystifying common misconception about the prevalence of Legionella bacteria
There is a common misconception that Legionella is only found in air conditioners and water towers - however, a new study has found people are likely exposed to the bacteria through other sources, including through soil.
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NewsResearchers develop first-of-its-kind RNA tool to advance cancer and infectious disease research and treatment
Scientists have developed a powerful tool capable of scanning thousands of biological samples to detect transfer ribonucleic acid (tRNA) modifications — tiny chemical changes to RNA molecules that help control how cells grow, adapt to stress and respond to diseases such as cancer and antibiotic‑resistant infections.
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NewsAre probiotics worth the cost to prevent infection after a colon removal surgery?
A study found that taking an 8-strain probiotic daily may reduce the risk of pouchitis, a common inflammatory condition that occurs after colon removal surgery for ulcerative colitis, but the treatment may not be worth the cost depending on a patient’s likelihood of flare-ups.
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NewsOne dose of antibiotic treats early syphilis as well as three doses
Researchers have found that a single injection of the antibiotic benzathine penicillin G (BPG) successfully treated early syphilis just as well as the three-injection regimen used by many clinicians. These findings from a late-stage clinical trial suggest the second and third doses of conventional BPG therapy do not provide a health benefit.
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NewsCARB-X to support lower respiratory tract infection diagnostic by Zeteo
CARB-X has awarded Zeteo Tech, Inc. US$1M to execute a workplan for its noninvasive diagnostic platform that aims to evaluate whether exhaled breath can diagnose lower respiratory tract infections (LRTIs) in high-risk populations within critical care environments.
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NewsClinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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NewsOne shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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NewsCARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.