All Clinical & Diagnostics articles – Page 3
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News
Clinical study shows that nasal spray containing azelastine reduces risk of coronavirus infection by two-thirds
In addition to showing a marked reduction in coronavirus infections, the azelastine group also displayed fewer symptomatic SARS-CoV-2 infections, a lower overall number of confirmed respiratory infections, and, unexpectedly, a reduced incidence of rhinovirus infections, another major cause of respiratory illness.
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One shot of RSV vaccine effective against hospitalization in older adults for two seasons
One shot of an RSV vaccine protects adults ages 60 or older from RSV-associated hospitalization and critical illness during two consecutive RSV seasons, according to a new study.
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CARB-X backs neonatal sepsis diagnostic platform by Quantamatrix
CARB-X has awarded QuantaMatrix Inc. US$2.85M to execute a workplan to develop its rapid diagnostic platform to detect sepsis, especially in vulnerable neonates. The test aims to deliver results within just 6 hours from very small blood samples of 1 to 2 milliliters.
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New sepsis diagnostic could reduce critical time to save patients
A new diagnostic method would confirm sepsis infections earlier, cutting critical hours in the “race against time” to save patients’ lives. The process uses a centrifuge to separate bacteria from blood cells, and automatic microscopy for detection.
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Guideline on respiratory infections in leukemia revised
People with leukemia have a weakened immune system due to the disease itself and treatment, which leads to an increased susceptibility to infections. In a revised guideline, experts summarize the findings of the past ten years on all viruses that cause respiratory infections.
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GI tumor microbes may predict prognosis and inform treatment
Intratumor microbes can play a role in disease progression and response to treatment. Researchers have identified core tumor microbiota associated with disease progression and risk, developing a microbiota-based risk score that can predict response to therapy.
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Gut bacteria can reveal colorectal cancer
Researchers identified all human gut bacteria to a level of detail that uncovers the physiological importance of the different microbial subgroups. This inventory was then used to detect the presence of colorectal cancer according to the bacteria present in simple stool samples.
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Careers
Spore.Bio: why now is finally the time for fast, AI-powered microbial detection
For decades, microbial detection and quantification have been a persistent bottleneck across industries. Today, the landscape is shifting.
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A microbial DNA signature differentiates two types of cancer in the liver
Researchers have identified a microbial DNA signature in blood plasma that reliably differentiates primary liver cancer from colorectal cancer that has spread to the liver (metastatic colorectal cancer).
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One universal antiviral to rule them all?
Taking inspiration from a rare mutation that makes people impervious to viral diseases, a researcher is developing a therapy that could bestow this superpower on the rest of us. The mutation causes a deficiency in an immune regulator called ISG15.
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CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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Mount Sinai creates first manual for treating infection-associated chronic illness for clinicians
Mount Sinai has launched the country’s first clinical manual for treating infection-associated chronic illnesses (IACIs). This comprehensive guide, prepared by the Cohen Center for Recovery From Complex Chronic Illnesses, part of the Department of Rehabilitation and Human Performance, will help clinicians better diagnose and care for patients with conditions such ...
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Bacterial protein therapy shows promise as first-ever antidote for carbon monoxide poisoning
Researchers have engineered a new molecule that appears promising as an effective antidote for carbon monoxide poisoning with fewer side effects than other molecules currently being tested.
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As school returns, so do infections & asthma emergencies. Where kids live can make it worse
A new study highlights how neighborhood conditions shape the seasonal surge of virus-triggered asthma emergencies. It found that children in under-resourced communities face sharply higher rates of asthma flare-ups tied to viral infections during the first weeks of school.
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Portable spectroscopy enables detection of vaginal microbes
Surface-enhanced Raman spectroscopy can rapidly and noninvasively detect specific bacterial species in vaginal fluid, enabling early identification of microbiome imbalances.
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Fast, accurate, low-cost diagnostics - and no lab required
Researchers have developed a breakthrough diagnostic tool that could transform how quickly and reliably we detect illnesses like COVID-19, Ebola, AIDS or Lyme disease. The test uses just a single drop of blood, costs a couple of dollars and delivers results in only 15 minutes.
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Multidrug-resistant bacteria spread from war-zone hospitals to other countries
After Russia’s full-scale invasion, thousands of patients were transferred from Ukraine to other European countries. Researchers in Helsinki found that 8% of Ukrainian refugees had been hospitalised due to war injuries. Almost 80% of them carried multidrug resistant bacteria.
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Researchers identify a potential biomarker for long COVID
Researchers have identified a potential biomarker for long COVID. The study results detail the detection of SARS-CoV-2 protein fragments within extracellular vesicles (EVs) — tiny, naturally occurring packages that help cells share proteins, metabolites, and other materials.
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New hydrogel-based treatment accelerates infected wound healing and balances skin microbiota
A novel ε-poly-L-lysine-loaded sodium-alginate/gelatin hydrogel (PSG15) has shown exceptional promise in accelerating the healing of infected wounds. The injectable hydrogel delivers antibacterial properties while regulating macrophage polarization and stabilizing the skin microbiota.
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M42 announces breakthrough results for its AI-powered tuberculosis screening
A new study is among the largest real-world clinical validations of an AI-driven healthcare solution to date, analyzing over one million chest X-rays (CXRs) to evaluate the efficacy and scalability of AI in TB screening.