All Clinical & Diagnostics articles – Page 3
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NewsBacteria found in lung tumors may boost immune response to cancer
New preclinical study shows bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite.
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NewsCommon virus rewires energy metabolism in human neurons
Advanced optical imaging techniques reveal viral infection reshapes neuron metabolism long before major cell damage appears.
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NewsBladder infection after brain injury worsens cognitive problems
New research shows urinary tract infections following a moderate brain injury can worsen cognitive problems caused by the injury.
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NewsFirst 24 hours after viral infection are critical
New research suggests that the first 24 hours after viral infection is critical in determining infection severity.
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NewsNew discovery could help scientists fight deadly fungal infections
Researchers have discovered that the bacterial antibiotic ‘gladiolin’ can disarm Candida albicans, one of the leading causes of life-threatening fungal infections, opening new avenues for developing life-saving treatments.
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NewsToo much RNA can starve cells of energy
Researchers uncover a link between excess RNA and mitochondrial damage — revealing new insights into viral infections, aging and RNA-based therapeutics.
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NewsNext-gen mRNA therapeutics get a new delivery vehicle
Researchers have developed a novel way of delivering circular RNA into cells, paving way for long-lasting mRNA-based therapeutics including cancer vaccines and obesity treatments.
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NewsPreventing the accumulation of mRNA-loaded lipid nanoparticles in the liver
New research has developed a novel coating agent that prevents lipid nanoparticles from accumulating in the liver—a major practical challenge when using lipid nanoparticles in vaccines and immunotherapies.
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NewsPre-existing antibodies linked to different immune responses after influenza vaccination
New study highlights how previous exposure to influenza viruses and vaccines can leave behind pre-existing antibodies, which may influence how the immune system responds to later vaccination.
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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NewsGut-pancreas immune crosstalk may offer new therapeutic strategies for pancreatic cancer
A new study reports that immune responses produced in lymph nodes shared by the liver, pancreas and intestine shape T-cell tolerance. This cross-organ immune rewiring increases T-cell infiltration into pancreatic tumors, pointing to potential new approaches for hard-to-treat pancreatic cancers.
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News‘Known’ TB gene springs to action under stress, with an unexpected biological role
New research has discovered that one of TB’s supposedly “known” genes has a completely unexpected biological role, with far-reaching implications.
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NewsPreventive TB treatment for individuals with HIV shown to be effective in real-world settings
A new study has evaluated the real-world impact of TB preventive treatment in six countries with high TB and HIV rates and highlights the importance of preventive treatment in reducing deaths caused by a curable disease.
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NewsAlbumin is prevented from crossing the placenta – opening opportunities for design of long-acting biologic medicines
Researchers have uncovered that the placenta distinguishes between antibodies and albumin, a finding that may reshape the future design of biologic medicines with reduced fetal exposure.
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NewsCell ‘invisibility cloaks’ could offer side-effect-free diabetes treatment
New research suggests manufacturing cells an “invisibility cloak” out of a jelly-like material known as hydrogel, may offer an easier, less damaging treatment pathway for people with diabetes undergoing cell therapy.
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NewsUC San Diego receives $12.3 million grant to study the intersection of HIV and methamphetamine use
A newly funded programme aims to use a multidisciplinary approach focused on improving the clinical care and brain health of people with HIV who also have an active methamphetamine use disorder.
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NewsStable RNA elements open new possibilities for mRNA therapeutics
New research has discovered compact viral RNA elements that can make mRNA more stable, and could provide a simple way to develop longer-lasting and more efficient mRNA technologies for vaccines and other RNA-based therapeutics.
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NewsCells use a little-known molecule to protect themselves from iron overload
New research shows that cells rely on an unexpected protector against elevated iron levels: small molecules called polyamines. These small molecules act like storage lockers for iron, safely holding the metal in a non-reactive state until cells need it.
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NewsNovel AI model accurately detects key gene mutations and predicts biomarkers across 32 cancer types
Researchers have developed a novel AI model capable of predicting cancer subtypes, specific genetic mutations, and survival outcomes across 32 different cancers.
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NewsImmune molecules play a limited role in ALS progression
New research indicates that immune-related molecules change in motor neurons affected by amyotrophic lateral sclerosis (ALS), but they do not appear to be major drivers of disease progression.