All Clinical & Diagnostics articles – Page 6
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NewsNew gel-based system allows bacteria to act as bioelectrical sensors
Researchers have developed a safe bioelectronic sensor that allows for effective electronic communication even in liquid environments. The system uses the naturally occurring polymer chitosan, acting as a kind of shell to keep the bacteria from escaping.
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NewsWebinar: Unraveling periprosthetic joint infection
The free ‘Unraveling Periprosthetic Joint Infection’ webinar on March 25 explores one of the most challenging complications in modern orthopedic medicine, sitting at the intersection of microbiology, surgery, and patient care.
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NewsDengue vaccine remains 80.5% effective against severe cases after five years
The tetravalent dengue vaccine was 80.5% effective against severe dengue cases with warning signs over a five-year period. Overall, the vaccine was 65% effective in preventing symptomatic dengue (caused by any serotype) during the five years of monitoring.
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NewsMpox immune test validated during Rwandan outbreak
An antibody test for the infectious disease Mpox was successfully developed during the new clade 1b outbreak in Rwanda, the first time that an assay of its kind has been validated within this setting.
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NewsScientists identify more effective way to detect poultry viruses in live markets
Scientists have found that viruses circulating in live poultry markets can be detected more effectively by sampling the surrounding environment than by testing individual birds. The study shows that environmental sampling can uncover a broader range of poultry viruses.
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NewsStudy warns of underrecognized Lassa Fever threat with global implications
A new study shows an urgent need for improved detection and treatment of Lassa fever. The study in Liberia found a high prevalence of Lassa fever among febrile admissions: 11% of patients with fever had Lassa fever despite not being suspected clinically.
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NewsGut microbiome connected with heart disease precursor
Before the onset of cardiovascular disease symptoms, people often develop dyslipidemia, or abnormal levels of lipids in the blood. Microbiologists have identified microbial taxa more likely to be found in people with dyslipidemia than in people with healthy levels of cholesterol and triglycerides.
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NewsThermo Fisher Scientific launches new color-based culture media to help detect Candida infections faster
Thermo Fisher Scientific today announced the launch of Thermo Scientific™ Brilliance™ Candida 2 Agar and Spectra™ Candida Agar, new color-based (chromogenic) culture media to help laboratories quickly detect and differentiate clinically important Candida species.
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NewsCell-free DNA offers early warning for bloodstream infections in kids with leukemia
Researchers show that microbial cell-free DNA sequencing can predict bloodstream infections in children with leukemia days before the symptoms appear. Plasma microbial cell-free DNA sequencing (mcfDNA-Seq) offer a potential approach to protecting vulnerable patients by allowing treatment to start before the patient gets sick.
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NewsEnhanced inner ear tropism of Adeno-Associated Virus (AAV) vectors via peptide display on AAV1 capsid
Researchers improving efficiacy of AAV)-mediated gene therapy for the inner ear screened and inserted short peptide motifs onto the surface of the AAV1 capsid. These engineered vectors achieved markedly higher transduction rates in inner ear hair cells and supporting cells.
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NewsBiomarkers indicating higher liver cancer risk in chronic hepatitis B patients identified
Researchers have identified Hepatitis B RNA serum levels as a biomarker that more accurately stratifies risk of liver cancer in individuals who have been functionally cured of chronic hepatitis B.
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Long ReadsRethinking Blastocystis: a One Health perspective on a common and controversial gut protist worth our attention
Here’s the reality: a stool report that reads “Blastocystis detected” still provokes strong reactions. Some clinicians worry and reach for antibiotics. Some laboratories add a note about “uncertain significance.” Patients search online and find polarised claims ranging from harmless commensal to stealth pathogen. The truth is more nuanced and more ...
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NewsGut health home-testing kit outcomes vary between kits and manufacturers
Results and health assessments from gut microbiome home-testing kits vary whether they are produced by the same or different manufacturers. The findings on testing kits from seven providers highlight the need for caution when interpreting or acting on test results, according to the authors.
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NewsSingle daily pill shows promise as replacement for complex, multi-tablet HIV treatment regimens
A phase 3 clinical trial has shown that a new, daily oral tablet that combines two current HIV treatment medications – bictegravir and lenacapavir (BIC/LEN) – may simplify treatment significantly for people with HIV who currently take very complex treatments.
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NewsUrinary tract infections can trigger delirium and worsen dementia
Urinary tract infections can pose serious risks for older adults, particularly those with Alzheimer’s disease and other forms of dementia. In older patients, a common UTI can trigger delirium, a medical emergency marked by sudden confusion and altered awareness.
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NewsNew study finds sex and menopause-based differences in presentation of early Lyme disease
In a new study, researchers found that male and female patients with early Lyme disease present with different signs of the disease in the symptoms they report, their physical exams and their laboratory test results.
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NewsScientists find that silencing bacteria can worsen heart infections
By studying a bacterium responsible for a severe heart infection, the scientists show that disrupting bacterial communication can be associated with adverse clinical outcomes. These findings open the door to more targeted therapeutic strategies against this type of infection.
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NewsFirst evidence of fungal pathogen becoming more deadly when co-infected with tuberculosis
Co-infection of Mycobacterium tuberculosis, together with Cryptococcus neoformans, is a grave public health concern, increasing the risk of death significantly. Researchers have found that in the presence of Mycobacteria, the fungus changed its cell density, cell diversity, and capsule size.
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NewsNew single-cell transcriptomic clock reveals intrinsic and systemic T cell aging in COVID-19 and HIV
Scientists developed a new single-cell transcriptomic clock called T immune cell transcriptomic clock (Tictock) to measure aging in specific immune cells. They found that in patients with acute Covid-19, the infection increased the biological age of naïve CD8 T cells.
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NewsScientists home in on Acinetobacter baumannii’s resistance evolution
Scientists have found a way to understand how Acinetobacter baumannii is evolving - and how best to strategize a fight against it. They have produced a huge whole-genome look at the rise of this resistance, pointing the way to new strategies in staying ahead of the pathogen.