All Clinical & Diagnostics articles – Page 5
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NewsExtracellular vesicle RNAs offer new hope for diagnosing and treating chronic inflammatory bowel disease
Extracellular vesicle-associated RNAs can serve as non-invasive biomarkers for early inflammatory bowel disease detection and disease monitoring, and also hold great potential as targets for next-generation targeted therapies, according to a new review.
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NewsMethod for amplifying the full genome of human papillomavirus 16 uses overlapping extension polymerase chain reaction
Human papillomavirus (HPV) is a double-stranded circular DNA virus with a genome of approximately 7–8 kb. A new study aims to establish an overlapping extension polymerase chain reaction method for the amplification of the entire genome of HPV16.
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NewsRapid and visual on-site detection system for Epizootic Hemorrhagic Disease Virus
Epizootic Hemorrhagic Disease (EHD), a vector-borne disease affecting both wild and domestic ruminants, is transmitted by biting midges of the genus Culicoides. Researchers developed a rapid and visual test strip for EHDV RNA detection based on RT-ERA and CRISPR-Cas12a.
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OpinionWhy chromogenic media matters when testing for invasive pathogens: Could the cheapest plate be an expensive decision?
Chris Armstrong, President of Microbiology, Thermo Fisher Scientific, argues that laboratories should stop judging fungal culture media on unit price alone.
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NewsBlood test using artificial intelligence paves the way for early diagnosis of leprosy
A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. The method showed potential for identifying the disease in its initial stages, when symptoms are subtle and traditional laboratory tests often fail.
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NewsNovel treatment protocol targets the deadliest cases of C. difficile infection
A new study demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile infection.
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NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
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NewsLong COVID associated with increased risk of cardiovascular disease
People with long COVID are at increased risk of developing cardiovascular disease, according to a new study. Women with long COVID had just over twice the risk of receiving a cardiovascular diagnosis compared with women without long COVID. Men had approximately a third higher risk.
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NewsSimple blood test for gut bacteria metabolites could spot dementia years earlier
Scientists have discovered that subtle changes in the blood may reveal the earliest signs of cognitive decline long before symptoms become obvious.These changes are caused by chemicals produced by gut bacteria - reinforcing the idea that the gut–brain connection plays an important role in early memory changes.
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NewsRapid urine test could select UTI antibiotics within hours
Patients with urinary tract infections (UTIs) could receive the right antibiotic far sooner, thanks to a new test that produces results within hours rather than days.
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NewsCall for evidence: Why has the promise of personalised medicine failed to materialise on the ground?
A new inquiry by the UK Parliament’s Science and Technology Committee investigates why the NHS adoption of the UK’s cutting-edge life sciences innovations often fails - and what could be done to fix it. Members of AMI could be just the people to provide answers.
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NewsDramatic reduction in prescribing of hepatitis C antivirals may leave many curable patients untreated
A new study analyzed a large national prescription database to estimate hepatitis C treatment courses over time and trends by patient and prescriber characteristics from 2013–2025. Prescriptions rose rapidly after direct-acting antivirals first became available, peaking in 2015, but then declined sharply through 2025.
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NewsSimple antiseptic can reduce newborn infections
A new Cochrane review finds that chlorhexidine likely cuts umbilical cord infection rates by about 29% in low- and middle-income countries, and may reduce newborn deaths.
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NewsWhy is vaccination for target populations plummeting in the UK? Share your insights!
As a group of leading UK health experts launches a new Commission on Access to Vaccines to understand why access levels are falling across the UK, Applied Microbiology International is calling on members to share their insights on childhood vaccinations.
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NewsWHO recommends new diagnostic tools to help end TB
On World TB Day, WHO is urging countries to accelerate action to end tuberculosis (TB) and expand access to lifesaving services by using new innovations such as diagnostic tests that can be used near the point-of-care and tongue swabs that can help detect the disease faster.
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NewsHKU innovations achieve recognition at the 51st International Exhibition of Inventions at Geneva
The University of Hong Kong (HKU) secured 46 awards at the 51st International Exhibition of Inventions of Geneva, including recognition for a project aiming to gain immunity against the three major respiratory viruses through home-based toothbrushing.
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NewsStudy shows breath test can confirm bacterial infection
A study shows how molecules that are only broken down by infecting bacteria, and not by gut bacteria, can be used to confirm infection. By enriching these molecules with a naturally occurring carbon isotope, the researchers found that carbon dioxide produced when they break down is easily detected in a breath test.
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NewsNovel biosensing platform enables fingertip blood-based micro-volume t-cell immune monitoring
A new platform, known as Tip Optofluidic Immunoassay Interferon-Gamma Release Assay (TOI-IGRA), could revolutionize how people monitor their immune health. The platform allows for the precise quantification of pathogen-specific T-cell responses using a mere 15-25 μL of fingertip blood.
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NewsPrototype breath tests spot bacterial infections in minutes
Researchers have adapted the long-used breath test for Helicobacter pylori, a bacterium that causes a common stomach infection, expanding the technology’s capabilities to detect a broader range of bacterial infections.
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NewsTrace levels of food pathogen do not always translate to health risk, says study
Ultra-sensitive food safety tests may drive food waste and unavailability with limited public health benefit, according to a study. These food safety measures and ultra-sensitive tests may drive edible food being thrown away, excessive packaging, and extra costs for consumers.