All Clinical & Diagnostics articles – Page 2
-
NewsGut microbiome changes may signal Parkinson’s disease risk
Scientists have found that people with Parkinson’s disease have a distinctive makeup of gut microbes, as do healthy individuals who are genetically at risk of Parkinson’s disease. This could help to develop tests to reveal a person’s risk of developing Parkinson’s disease.
-
NewsOral-gut axis points to salivary biomarkers for early gastric cancer detection
A recent study has identified distinct microbial “signatures” within the oral cavity and gut that serve as robust biomarkers for the early detection of gastric cancer (GC). Research shows how specific lactic acid-producing bacteria (LAB) migrate from the mouth to colonize the gastrointestinal tract.
-
NewsNew biosensor for detecting active tuberculosis
A research team is developing a sensor that paves the way for the rapid, selective and cost-effective detection of active tuberculosis. The device detects the presence of a protein secreted by Mycobacterium tuberculosis, the bacterium that causes the disease.
-
NewsThe cold virus ‘hides’ and multiplies in the tonsils and adenoids, even in people without symptoms
A study reveals that tissues such as the tonsils and adenoids can serve as hiding places for the rhinovirus, which causes the common cold. The pathogen can persist in these tissues for long periods, be transmitted unexpectedly, and trigger new outbreaks of the disease.
-
NewsStudy finds blood pressure drug effective for treating antibiotic-resistant bacteria
A new study reports that a drug used to lower blood pressure could also be the basis of a promising new treatment for methicillin-resistant Staphylococcus aureus (MRSA). Candesartan cilexetil not only killed MRSA bacteria at different growth stages, but also reduced the formation of biofilms.
-
NewsLong-term cure rates for multidrug-resistant tuberculosis much better than expected
A new national cohort study from Latvia provides important insights into the treatment of multidrug-resistant tuberculosis (MDR-TB). The study shows that long-term disease-free survival rates are significantly higher than previous standard indicators suggest.
-
FeaturesClinical considerations for the next pandemic: challenges facing Japan and strategic preparedness
Multiple global pandemics over the past century – the Spanish influenza (1918), Asian influenza (1957), Hong Kong influenza (1968), H1N1 influenza (2009), and COVID‑19 (since 2019) – have increasingly underscored the necessity for healthcare systems worldwide to be resilient, rapidly responsive, and forward‑facing.
-
NewsColor test ‘sniffs out’ dangerous staph strains fast
Researchers have developed a rapid colour-changing test that can distinguish between different strains of golden staph, including those likely to be virulent and antibiotic resistant.
-
NewsGlobal strategy to combat drug‑resistant fungi is about to change
An increasing number of fungi are becoming resistant to medication, posing serious risks for patients with weakened immune systems. That is why fifty researchers from around the world are calling for action against drug‑resistant fungi.
-
NewsUltrasensitive test reveals evidence of previously undetected tuberculosis in Boston Hospital patients
Researchers have discovered an unexpectedly high prevalence of Mycobacterium tuberculosis DNA (TB DNA) in patients hospitalized in Boston, suggesting that tuberculosis disease may be significantly underdiagnosed in the United States.
-
NewsShorter antibiotic courses show similar outcomes to longer use for some pneumonia patients
A multicenter target trial emulation found that for eligible patients hospitalized with community-acquired pneumonia (CAP), health outcomes were similar whether they received a three- to four-day course of antibiotics or a course lasting five days or more.
-
NewsExtracellular vesicle RNAs offer new hope for diagnosing and treating chronic inflammatory bowel disease
Extracellular vesicle-associated RNAs can serve as non-invasive biomarkers for early inflammatory bowel disease detection and disease monitoring, and also hold great potential as targets for next-generation targeted therapies, according to a new review.
-
NewsMethod for amplifying the full genome of human papillomavirus 16 uses overlapping extension polymerase chain reaction
Human papillomavirus (HPV) is a double-stranded circular DNA virus with a genome of approximately 7–8 kb. A new study aims to establish an overlapping extension polymerase chain reaction method for the amplification of the entire genome of HPV16.
-
NewsRapid and visual on-site detection system for Epizootic Hemorrhagic Disease Virus
Epizootic Hemorrhagic Disease (EHD), a vector-borne disease affecting both wild and domestic ruminants, is transmitted by biting midges of the genus Culicoides. Researchers developed a rapid and visual test strip for EHDV RNA detection based on RT-ERA and CRISPR-Cas12a.
-
OpinionWhy chromogenic media matters when testing for invasive pathogens: Could the cheapest plate be an expensive decision?
Chris Armstrong, President of Microbiology, Thermo Fisher Scientific, argues that laboratories should stop judging fungal culture media on unit price alone.
-
NewsBlood test using artificial intelligence paves the way for early diagnosis of leprosy
A new blood test combined with a standardized questionnaire and artificial intelligence may transform the way leprosy is diagnosed in Brazil. The method showed potential for identifying the disease in its initial stages, when symptoms are subtle and traditional laboratory tests often fail.
-
NewsNovel treatment protocol targets the deadliest cases of C. difficile infection
A new study demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides difficile infection.
-
NewsCharacteristics of CD4+T-cell reduction and pulmonary infections in critically ill immunocompromised patients
A new study investigates the relationship between reduced CD4+T-cell counts and lung infections in immunosuppressed patients admitted to intensive care units (ICUs).
-
NewsLong COVID associated with increased risk of cardiovascular disease
People with long COVID are at increased risk of developing cardiovascular disease, according to a new study. Women with long COVID had just over twice the risk of receiving a cardiovascular diagnosis compared with women without long COVID. Men had approximately a third higher risk.
-
NewsSimple blood test for gut bacteria metabolites could spot dementia years earlier
Scientists have discovered that subtle changes in the blood may reveal the earliest signs of cognitive decline long before symptoms become obvious.These changes are caused by chemicals produced by gut bacteria - reinforcing the idea that the gut–brain connection plays an important role in early memory changes.