All Clinical & Diagnostics articles – Page 2
-
NewsReal-time brain monitor detects infections earlier
A research team has created a new monitoring system to save lives and significantly reduce health-care costs in brain-injury cases through the early detection of infections in intensive care units. NeuroSense connects to drainage lines to detect biomarkers of infection.
-
NewsNew fluorescent nanosensor enables first-of-its-kind detection of key gut health biomarker
Researchers have developed a novel fluorescent nanosensor capable of rapidly detecting indole-3-propionic acid (IPA), an emerging biomarker linked to gut health and disease. The sensor produces a rapid optical readout within minutes, offering a significantly faster and more accessible alternative to conventional analytical techniques.
-
NewsBehind the diagnosis: How laboratory testing guided a complex histoplasmosis case
A diagnosis of histoplasmosis forced a teenager with juvenile arthritis onto an uncertain path, one defined by months of treatment, recovery, and a long-term course of antifungal therapy expected to last up to three years. Histoplasma capsulatum, a dimorphic fungus that causes histoplasmosis, found its way into her lungs.
-
NewsPost-discharge antibiotics may offer limited benefit after pediatric appendicitis
Acute appendicitis is one of the most common surgical emergencies among children, and complicated acute appendicitis (CAA), including perforated or gangrenous disease, carries a higher risk of infection and longer hospitalization. While intravenous antibiotics during hospitalization are standard practice, the role of oral home antibiotics (OHA) after discharge remains controversial. ...
-
NewsPrecigen presents new long-term durability data for PAPZIMEOS, recently granted seven-year market exclusivity
Precigen, Inc. has announced updated long-term follow-up data from the pivotal study of PAPZIMEOS™ (zopapogene imadenovec-drba) for the treatment of adults with recurrent respiratory papillomatosis (RRP).
-
NewsSkin-to-skin care may save newborn lives
Kangaroo mother care, first introduced as an alternative to insufficient incubator care, combines skin-to-skin contact, exclusive breastfeeding, early discharge, and follow-up support. A new review case makes the case for treating iKMC not as an optional add-on, but as a core part of neonatal care for eligible preterm and low-birth-weight infants.
-
NewsResearchers aim to improve access to high-quality research and biomanufacturing tools in resource-limited settings
Researchers have demonstrated the effectiveness of a suite of low-cost, portable biotechnology tools designed to improve access to laboratory research and diagnostics in resource-limited settings.
-
NewsStudies point to new way to fight potentially deadly Valley Fever
To better understand why Valley Fever spreads in some individuals, researchers found that patients with severe illness had an abnormal immune response. In some cases, the immune system was overactive; in other cases it was underactive.
-
NewsGut microbiome clusters may help predict inflammatory bowel disease severity and progression
A new study reports that the gut microbiome of IBD patients can be grouped into distinct compositional “cluster types” associated with disease severity and progression risk. These reflect higher-order microbial community organization rather than variation in individual bacterial species.
-
NewsNew urine test for microbial metabolites offers simple way to screen for autism in children
Scientists have developed a new screening tool to test urine for 17 microbial metabolites in children ages 2 to 11 years. By measuring these compounds in urine, they discovered that they could distinguish children with autism from typically developing children in their study groups with high accuracy.
-
NewsNP14 aptamer: A novel biosensing recognition element for mutation-resilient SARS-CoV-2 detection
New research investigated a novel DNA aptamer, NP14, and developed an innovative dual-mode biosensing platform to achieve highly sensitive, mutation-resilient viral detection.
-
NewsAutomated EHR alert improved hepatitis B monitoring rates at a primary care clinic
In May 2024, an urban safety-net primary care clinic noted the appearance of a new “care gap” alert in their Epic electronic health record (EHR) system that flagged patients with hepatitis B who were overdue for one blood test, the hepatitis B DNA test.
-
NewsICU pneumonia has mortality rates of 37% to nearly 60% in middle-income countries. In high-income countries, rates are16% to 26%
A scientific review evaluated outcomes of adults with community-acquired pneumonia (CAP) admitted to intensive care units (ICUs) in middle-income countries. In contrast to high-income countries, where mortality ranges from 16% to 26%, the study found significantly higher rates in the countries analyzed.
-
NewsNASCAR star’s death shows how sepsis can kill anyone if not caught
Kyle Busch won more races than any driver in NASCAR history. But his own race ended far too soon, cut short by sepsis at the age of 41 after a case of pneumonia.
-
NewsPegylated interferon-based treatment improves response rates in immune-tolerant patients with chronic hepatitis B
A new study aimed to investigate the efficacy and predictive factors of a pegylated interferon (Peg-IFN)-based treatment strategy in IT patients with chronic HBV infection.
-
NewsHPV self-collection boosts cervical cancer screening rates
The first major U.S. rollout of HPV self-collection shows benefits for patients and providers, including fewer pelvic exams and better follow-up for HPV-positive results.
-
NewsHost-based antifouling gold nanotube sensor for the selective detection of mechanically sensitive serotonin release in intestinal mucosa
A new study report a stretchable electrochemical sensing platform with high deformation insensitivity and strong antibiofouling capability. The platform enables in situ capture of dynamic small-molecule chemical signals in the gut, and revealed a new mechanism underlying enhanced intestinal mechanosensation under microbe-related stimulation.
-
NewsOptical method concentrates microscopic targets for faster, more sensitive detection
Researchers have developed a light-driven technique that quickly amasses thousands of bacteria into a single spot, boosting detection speed and sensitivity. Their approach paves the way for earlier diagnosis of disease.
-
NewsEstablishing a regulatory framework for phage therapy in China
A new study summarizes the current regulatory frameworks for phage therapy in Western countries and China, and proposes a pathway for establishing a regulatory framework that enables safe and effective clinical application of phage therapy in China.
-
NewsImplantable living materials autonomously deliver therapeutics using contained engineered bacteria
Researchers have introduced an implantable “living material” that contains bacteria that sense infections. It can release these therapeutic molecules on demand, while keeping them physically separated from the surrounding tissue.