All Japan articles – Page 2
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NewsHealthier, tastier kelp: food scientists boost nutrition and flavour of kombu
A team of food scientists has found a way to unlock the trapped nutrients in the edible seaweed, kombu, and replace the strong odours with more appealing scents, directly overcoming the two major challenges – limited nutrient bioaccessibility and poor sensory experience.
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NewsMethane’s missing emissions: The underestimated impact of small sources
Although efforts are being made to reduce the contribution of big polluters to methane in Japan, new research suggests that smaller sources are vastly underestimated in the Osaka metropolitan area. The team found unaccounted emissions from numerous small sources, including restaurants, commercial facilities, and private residences.
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NewsNew findings on infection with the Epstein-Barr virus
Researchers have identified genetic and non-genetic factors that help the body fight the Epstein-Barr virus. Using a new technique, they were able to estimate the amount of EBV in the blood and find correlations in large health data sets – for example, an increased viral load in people with HIV infections, but also in smokers.
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NewsScientists discover ‘bacterial constipation’, a new disease caused by gut-drying bacteria
Scientists have found two gut bacteria working together that contribute to chronic constipation. The duo, Akkermansia muciniphila and Bacteroides thetaiotaomicron, destroy the intestinal mucus coating essential for keeping the colon lubricated and feces hydrated.
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NewsNew antibody–drug conjugate strategy to block HIV infection
New antibody–drug conjugates (ADCs) combine a CD4 mimic with neutralizing antibodies for enhanced suppression of HIV infection. By targeting the gp120 on the viral envelope via a two-step mechanism, the ADCs effectively block viral entry.
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NewsRhododendron-derived drugs now made by bacteria
Bioengineered E. coli bacteria can now produce a group of compounds with anticancer, anti-HIV, antidiabetic and anti-inflammatory activities. The compounds, orsellinic acid-derived meroterpenoids, are produced by Rhododendron species.
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NewsStudy reveals how chills develop and support the body’s defense against infection
Researchers in Japan have identified the neural mechanism behind chills and the instinct to increase body temperature during infection.
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NewsTechnology transfer for Corallopyronin A successfully completed with Phyton Biotech
Phyton Biotech has successfully transferred the manufacturing process for the microbial production of Corallopyronin A (CorA). CorA is a novel anti-infective agent with the potential to address neglected tropical diseases.
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NewsGreen chemistry: Friendly bacteria can unlock hidden metabolic pathways in plant cell cultures
Co-culturing plant cells with harmless bacteria can expand the diversity of obtainable plant-derived compounds for pharmaceuticals, cosmetics, and agrochemicals, a new study shows.
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NewsVaping zebrafish suggest E-cigarette exposure disrupts gut microbial networks and neurobehavior
Researchers hope to spark broader public discussion on the health risks of e-cigarettes and provide scientific evidence to support a reassessment of existing regulations.
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NewsHow bacteria in the mouth may offer new clues to cognitive dysfunction in people with schizophrenia
An association between oral microbiota and cognitive performance in schizophrenia has been reported by researchers. The study shows that lower oral microbial diversity is associated with poorer cognitive function, with specific predicted microbial metabolic pathways potentially linked to this relationship.
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NewsNatural sunscreen compounds show potential to support skin health and blood pressure
Researchers have discovered that natural ‘sunscreen’ compounds found in algae and cyanobacteria may also support skin and heart health.
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NewsPros and cons of pesticides and fertilizers in real-world mandarin orange farms
Researchers examined how different kinds of pesticides and fertilizers affect mandarin oranges across Japan. Advanced statistical analysis showed that while reducing pesticides enhanced the diversity of microbes in the soil, it also led to an increase in fruit disease caused by leaf pathogens.
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NewsBacteria use wrapping flagella to tunnel through microscopic passages
A new study shows that certain symbiotic bacteria wrap their rotating flagella around their cell bodies to form a “screw thread.” This configuration lets them propel forward through one-micrometer-wide passages, such as those inside insect guts, that would otherwise trap or immobilize them.
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NewsSniffing out the cause of keratoderma-associated foot odor
The distinct foot odor that comes with the skin disorder Nagashima-type palmoplantar keratosis (NPPK) is caused by the overgrowth of a specific bacterial strain. Topical application of benzoyl peroxide restores balance in the bacterial skin flora, reducing the odor.
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NewsEngineering yeast to make rare anticancer saponins: reconstructing the complete biosynthesis of polyphyllin II
By combining plant transcriptomics, enzyme engineering, and synthetic biology, a new study demonstrates, for the first time, the full heterologous production of polyphyllin II in Saccharomyces cerevisiae.
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NewsDeadly to amphibians, a fungal strain emerged in Brazil and spread around the world
The fungal infection Batrachochytrium dendrobatidis is responsible for the decline of toad and frog populations across the globe. A new study has pinpointed the origin of the fungal strain.
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NewsScientists explore how gut bacteria alter the flavor of Black Ivory coffee beans
Coffee beans that pass through the digestive tracts of animals get their unique flavors from the activity of gut microbes, report researchers. Bacterial activity that reduces the pectin content of Black Ivory coffee could be the source of its smoother, chocolaty, and less bitter flavor.
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NewsNew study explores therapeutic potential of CRISPRCas3 genome-editing system
Scientists working on the genetic disease transthyretin amyloidosis evaluated the efficacy of the CRISPR–Cas3 system in safely achieving a permanent reduction of transthyretin (TTR) production through genome editing of the TTR gene.
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NewsResearchers revive failing antibiotics with two-faced Janus nanoparticles
Researchers have restored the power of failing antibiotics by combining them with two-sided nanoparticles, ultra-small building blocks of materials less than 100 nanometers across. The nanoparticles showed a remarkable ability to compromise bacterial cell walls, leaving them vulnerable to attack.