All Phage Therapy articles
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NewsNew phage editing technology could lead to alternative treatments for antibiotic-resistant bacteria
Scientists have developed a technology that lets them edit the genomes of phages in a streamlined and highly effective way, giving them the ability to engineer new phages and study how the viruses can be used to target specific bacteria.
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NewsDormancy defence systems show us why phages may not be the answer to everything
Toxin/antitoxin defence systems in bacteria need to be better understood if the potential of phage therapy is to be realised, a new review in Sustainable Microbiology suggests.
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NewsScientists unveil first complete image of the PARIS system
A new study explores the PARIS immune system, which bacteria use to protect themselves against viral infections and which stands for Phage Anti-Restriction Induced System.
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News3D shapes of viral proteins point to previously unknown roles
Scientists uncover an ancient immune-evading strategy shared by animal viruses and viruses that infect bacteria; findings may help in the development of new antiviral therapies.
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NewsInfected bacteria fight back with ‘hidden’ genes that halt cell growth, slow viral spread
Researchers have uncovered a surprising way bacteria defend themselves: when a bacterium is infected, bacterial enzymes that copy genetic information from RNA into DNA synthesize genes whose protein products help shut down cell growth.
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NewsCoinfecting viruses impede each other’s ability to enter cells
Scientists researching phage infection at the level of a single cell investigated whether the number of infecting phages that bind to the bacterial surface corresponds to the amount of viral genetic material that is injected into the cell.
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NewsHuman clinical study launched using phage lysin to eliminate staph in the nasal microbiome
A “first-in-human” study with the novel drug candidate HY-133 began on 10 July with the recruitment of clinically healthy volunteers who tested positive for Staphylococcus aureus colonisation of the nose.
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NewsResearchers unveil secrets behind phages’ flawless timing
New research is shedding light on how viruses ensure their survival by precisely timing the release of new viruses. The discovery offers a new theoretical framework for understanding these dynamic biological phenomena.
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NewsHarnessing big data helps scientists hone in on new antimicrobials
Scientists have detailed a new method of identifying antimicrobial enzymes from large datasets of bacterial proteins, which could provide a solution to antibiotic resistance.
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NewsResearchers develop a way to make lifesaving phages accessible, transportable and much easier to use
Researchers have developed a simple new way to store, identify, and share phages, making them more accessible to patients who need them.
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NewsPhage-derived enzyme targets biofilms to mitigate acute graft-versus-host disease
Scientists investigating acute graft-versus-host disease probe gut microbiome to detect presence of a bacteriophage-derived enzyme known as endolysin, exhibiting potent antibacterial activity specifically targeting E. faecalis.
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News‘Sacrifice’ of virus data clears the path to open a disease discovery pipeline
Researchers are analysing viruses in human populations – and on coral reefs – to build a robust method of identifying viruses in all animals, plants and environments, and to show the flexibility of the pipeline for future research.
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NewsPhage‐display tech boosts targeting ability of antimicrobial peptides against Staphylococcus aureus
Antibiotics are widely used in clinical treatment and animal production as an effective means to combat microbial infections. Antimicrobial peptides, as potential alternatives to antibiotics, have shown promising applications. Source: CDC/ Matthew J. Arduino/ Janice Haney Carr Under a very high magnification of 20,000x, this scanning electron micrograph ...
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CareersA day in the life of a phage expert
Nicolás Cifuentes is Head of Research Projects and Phages at PhageLab, Chile, which offers tailor-made solutions to control bacterial outbreaks in the livestock and poultry industries.
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NewsPlant bacteria deploy phage elements to wipe out the competition
A new study has found that plant bacterial pathogens are able to repurpose elements of their own phages to wipe out competing microbes, suggesting such elements could someday be harnessed as an alternative to antibiotics.
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NewsMalta hosts groundbreaking 7th World Conference on Targeting Phage Therapy 2024
The historic Corinthia Palace in Malta is set to host the 7th World Conference on Targeting Phage Therapy on June 20-21, 2024. This event will bring together the world’s foremost leaders and researchers in bacteriophage therapy, highlighting the growing importance and global interest in this innovative field. ...
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NewsInnovative phage lysin HY-133 enters phase I clinical study
HYpharm’s innovative preventive agent HY-133 has reached the first clinical trial phase. HY-133 is specifically effective against Staphylococcus aureus including multi-resistant strains and is intended to combat its colonisation in the nose.
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NewsSqueaks the cat makes full recovery after personalized phage therapy heals resistant wounds
A new study highlights the potential of phage therapy as an effective solution for antibiotic-resistant infections in veterinary practice, resulting in the complete healing of a persistent surgical wound after fourteen weeks.
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NewsVirocells: How the ‘home’ environment influences microbial interactions
Research into ocean virocells - bacteria infected by viruses, thus forming a new organism - has yielded fascinating new insights about how this merger of microbes affects, and is affected by, real-world surroundings.
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NewsSea zombies: Viruses keep the most common marine bacteria in check
The ocean waters surrounding the German island of Helgoland provide an ideal setting to study spring algae blooms, a focus of research at the Max Planck Institute for Marine Microbiology since 2009. Source: Jan Brüwer/Max Planck Institute for Marine Microbiology Sunset over the island of Helgoland in ...
