All Phage Therapy articles
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NewsResearchers find a gentler way to treat aggressive gum disease
Researchers have discovered that the primary bacterium driving gum disease carries an internal “genetic brake” that controls its own aggression. By locking this brake in place, future treatments could silence the pathogen while leaving beneficial bacteria untouched.
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NewsSilent enemies, smart weapons - switching off phage contamination using nanoparticles
Bacteriophages represent a serious threat to laboratories and industries that rely on bacterial cultures for production. Researchers have demonstrated an innovative solution that enables targeting the surface of bacteriophage through electrostatic interactions.
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NewsNew study reveals a minimalist bacterial defense that disrupts viral assembly
Researchers describe how a single protein named Rip1 recognizes bacteriophages, the viruses that infect bacteria, and cause infected bacteria to die prematurely, thereby ending the chain of transmission.
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NewsHow bacteria learned to target numerous cell types, revealed
A new study shows how bacteria adapted a virus-derived injection system to recognize and attach to many different types of cells. By identifying thousands of rapidly evolving receptor-binding proteins, the researchers explain how these systems can be retargeted in nature by swapping the part that binds to cells.
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NewsPIXL Max: Automated colony picker breaks records for speed and accuracy
With the latest innovation from the team at Singer Instruments, a new standard for speed and repeatability in microbial colony pickers has been achieved through the integration of cutting edge AI technologies.
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NewsNexaBiome accelerates development of novel diabetic foot treatment with Scottish Enterprise funding
UK biotechnology company NexaBiome Life Sciences Ltd has received continued funding from Scotland’s national economic development agency, Scottish Enterprise, to accelerate its breakthrough bacteriophage technology for the treatment of diabetic foot infections (DFIs).
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NewsGolden Gate method enables rapid, fully-synthetic engineering of therapeutically relevant bacteriophages
Researchers have described the first fully synthetic bacteriophage engineering system for Pseudomonas aeruginosa. In this method, researchers engineer bacteriophages synthetically using sequence data rather than bacteriophage isolates.
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FeaturesUnlocking the secrets of phages: DNA modification discoveries offer new weapons against antimicrobial resistance
Bacteria and their viral predator bacteriophages (phages) have coevolved for billions of years and are engaged in an endless arms race against each other. DNA modifications are among the most widespread defenses to block bacterial RM and CRISPR-Cas systems.
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NewsAboard the International Space Station, viruses and bacteria show atypical interplay
In a new study, terrestrial bacteria-infecting viruses were still able to infect their E. coli hosts in near-weightless “microgravity” conditions aboard the International Space Station, but the dynamics of virus-bacteria interactions differed from those observed on Earth.
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NewsScientists reveal how excess hydrogen triggers metabolic shifts and viral defense in syngas microbiomes
Syngas biomethanation—converting CO/CO₂/H₂ into renewable methane—relies on coordinated microbial interactions. A study reveals that excess hydrogen disrupts this balance, reducing methanogenesis efficiency and triggering major shifts in microbial metabolism and viral dynamics.
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News4 million euros for study with personalized phage therapy
UMC Utrecht has received a grant of 4 million euros for the first clinical study in the Netherlands involving a customized therapy with bacteriophages for patients with recurrent urinary tract infections.
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FeaturesBuilding integrated biobanks to defeat AMR in chronic wounds
Antimicrobial resistance (AMR) has evolved into a complex global health issue which has outstripped the development of new antibiotics and therapeutic strategies. The World Health Organisation (WHO) estimates 1.27 million deaths were attributed to AMR infections in 2019. By 2050, 10 million deaths are predicted at a cost of $100 ...
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NewsSingle-cell movies reveal how host physiology sets phage success - and how to time therapies
A new study outlines how an innovative imaging platform can be used to help uncover the reasons why phages succeed or fail when used to target bacterial infections.
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NewsVIRE: a global data platform to better understand viruses
Researchers have released a comprehensive viral genome database covering diverse ecosystems to advance the understanding of viral evolution and ecosystem functions.
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NewsHow reactive oxygen species target viruses differently: new clues for safer water disinfection
A new study systematically explored how reactive oxygen species (ROS) inactivate viruses with distinct structures. The results revealed clear heterogeneity: enveloped RNA viruses were most susceptible to oxidation, while double-stranded DNA viruses showed strong resistance.
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NewsMucosal virome and host transcriptome interactions reveal viral influence in colorectal polyp development
A new study has provided the first integrated mucosal virome-transcriptome landscape of colorectal polyps, the precursors of colorectal cancer, offering new insights into viral-host interactions at this early disease stage.
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NewsUnder The Lens: Callum Cooper explores how bacteriophages could revolutionise medicine - and how we get to that point
In a compelling new video interview from Applied Microbiology International’s ‘Under the Lens’ series, Dr. Callum Cooper shares fascinating insights into one of medicine’s most promising frontiers: phage therapy.
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VideoThe Microbiologist: Under the Lens | Episode 2
In our second episode, Dr Callum Cooper joins Professor Emmanuel Adukwu to talk about all things bacteriophage, from alternatives to antibiotics, social impact, and regulation.
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NewsDr José Luis Balcazar named as winner of John Snow Public Health Innovation Prize
Dr José Luis Balcazar, Senior researcher at the Catalan Institute for Water Research (ICRA-CERCA), Spain, has been named as the newest winner of the John Snow Public Health Innovation Prize.
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NewsFive new phages discovered in university’s Botanical Gardens
Five new bacteriophages have recently been discovered in the ponds of Lund University’s Botanical Gardens. Phages thrive wherever bacteria are found, which often means ponds and watercourses that are rich in organic material.