All Phage Therapy articles
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News
Spotlight on phage for a fascinating policy discussion
Scientists turned the spotlight onto the potential of phage in a recent AMI webinar that yielded a fascinating in-depth discussion that proved invaluable in clarifying the way forward. The ‘Phages for a Sustainable Future’ webinar has now been released as a video.
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Beyond viruses: Expanding the fight against infectious diseases
The newly renamed Gladstone Infectious Disease Institute has broadened its mission to address global health threats ranging from antibiotic resistance to infections that cause chronic diseases.
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Scientists develop a virus cocktail to combat superbugs
Researchers have developed a bespoke phage therapy, Entelli-02, a five-phage cocktail designed specifically to target Enterobacter cloacae complex (ECC), a group of bacteria responsible for severe, often difficult-to-treat infections.
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‘Microbial piracy’ uncovers new way to fight drug-resistant infections
Researchers have discovered how ‘pirate phages’ hijack other viruses to break into bacteria, sharing new genetic material for dangerous traits.
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Mushroom chemical teams with phages to deliver a one-two punch to MRSA
A chemical found in mushrooms can be teamed with bacteriophages to deliver a one-two punch to antibiotic-resistant infections, reveals a study presented at MLS Future Forum 2025.
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Zoo poo might hold the secrets to new medical treatments
Scientists are hoping the collection of poo from tigers, elephants, giraffes and other exotic animals, could contain the secret to finding new medical treatments. Although a waste product to the animals, hidden amongst it are thousands of phages which are potentially capable of fighting bacterial infections.
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CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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New insights could help phages defeat antibiotic resistant bacteria
Researchers have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance. The new research is the first to describe how a bacterial defence mechanism against phages, called Kiwa, works.
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Study of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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Careers
Petri dishes, phages, and public speaking - at the LAM ECS Research Symposium 2025
Rachael Barton and Luka Brajdić open up on their experiences of the Letters in Applied Microbiology ECS Symposium 2025 at the University of Liverpool on June 12.
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Study advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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The gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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Early career scientists gear up for LAM ECS Symposium next week
More than 100 delegates have now signed up for the Letters in Applied Microbiology Early Career Scientists Symposium 2025, a one-day event which is taking place in Liverpool on June 12.
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Global phage experts converge in Berlin to shape the future of antimicrobial medicine
The 8th World Congress on Targeting Phage Therapy (June 10–11, 2025) returns to Berlin, bringing together over 75 international speakers and contributors from 27 countries.
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Scientists uncover how certain cholera strains are so successful at evading phage attacks
A new study shows that a virulent lineage of cholera acquired multiple distinct bacterial immune systems that have protected it from diverse types of phages. This defense may have contributed to the massive scale of the Latin American epidemic.
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Phage expert Graham Hatfull elected as a Fellow of the Royal Society
Graham Hatfull, Eberly Family Professor of Biotechnology and HHMI Professor in the University of Pittsburgh Kenneth P. Dietrich School of Arts and Sciences, has been named a Fellow of the Royal Society.
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A turning point in medicine: phage therapy moves from promise to practice
From June 10–11, 2025, the international scientific and medical community will gather in Berlin for Targeting Phage Therapy 2025, the leading global event focused on translating phage research into clinical reality.
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Researchers find CRISPR is capable of even more than we thought
Researchers studying key immune components of some CRISPR systems have announced the newest CARF effector they’ve discovered, which they coined Cat1 - it can deplete a metabolite essential for cellular function.
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Scientist awarded $500,000 Gruber Genetics Prize for pioneering discoveries in bacterial immune systems
The 2025 Gruber Genetics Prize is being awarded to geneticist and molecular biologist Rotem Sorek, Ph.D., of the Weizmann Institute of Science, for his discoveries in the immune system of bacteria.
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Scientists reveal key bacterial immune mechanism
Researchers have uncovered a pivotal mechanism by which bacteria defend themselves against viral infection. Cyclic dinucleotides (CDNs), synthesized during activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism, trigger the filamentous assembly of phospholipase effectors, which execute the downstream immune response.