All Phage Therapy articles
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News CRISPR-based therapeutics hold potential to combat AMR and cure chronic viral infections, says GlobalData
CRISPR-based therapeutics show potential to combat antimicrobial resistance (AMR) and deliver functional cures for chronic viral infections, says GlobalData, a leading data and analytics company.
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NewsNew insights could help phages defeat antibiotic resistant bacteria
Researchers have worked out how bacteria defend themselves against viruses called phages and the new insights could be key to tackling antibiotic resistance. The new research is the first to describe how a bacterial defence mechanism against phages, called Kiwa, works.
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NewsStudy of water bodies frequented by wild birds reveals presence of antimicrobial resistance genes in nine in 10 samples
The first UK study to monitor antimicrobial resistance and influenza viruses in water bodies has revealed that 92% of samples contained genes for resistance to colistin, an antibiotic of last resort.
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CareersPetri dishes, phages, and public speaking - at the LAM ECS Research Symposium 2025
Rachael Barton and Luka Brajdić open up on their experiences of the Letters in Applied Microbiology ECS Symposium 2025 at the University of Liverpool on June 12.
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NewsStudy advances understanding of immune system’s crucial role in phage therapy
Scientists have assessed the effectiveness of phage therapy in treating pneumonia. What they discovered about the mechanisms behind phage therapy could inform treatments in clinical settings to help patients facing similarly stubborn infections.
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NewsThe gut’s secret weapon: viruses that heal
A comprehensive new review reveals how gut viruses interact with gut bacteria and host immunity, highlighting their roles in conditions like inflammatory bowel disease, colorectal cancer, and C. difficile infection. The findings offer a compelling case for harnessing the virome in novel therapies to reshape gut ecology and restore health.
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NewsEarly career scientists gear up for LAM ECS Symposium next week
More than 100 delegates have now signed up for the Letters in Applied Microbiology Early Career Scientists Symposium 2025, a one-day event which is taking place in Liverpool on June 12.
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NewsGlobal phage experts converge in Berlin to shape the future of antimicrobial medicine
The 8th World Congress on Targeting Phage Therapy (June 10–11, 2025) returns to Berlin, bringing together over 75 international speakers and contributors from 27 countries.
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NewsScientists uncover how certain cholera strains are so successful at evading phage attacks
A new study shows that a virulent lineage of cholera acquired multiple distinct bacterial immune systems that have protected it from diverse types of phages. This defense may have contributed to the massive scale of the Latin American epidemic.
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NewsPhage expert Graham Hatfull elected as a Fellow of the Royal Society
Graham Hatfull, Eberly Family Professor of Biotechnology and HHMI Professor in the University of Pittsburgh Kenneth P. Dietrich School of Arts and Sciences, has been named a Fellow of the Royal Society.
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NewsA turning point in medicine: phage therapy moves from promise to practice
From June 10–11, 2025, the international scientific and medical community will gather in Berlin for Targeting Phage Therapy 2025, the leading global event focused on translating phage research into clinical reality.
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NewsResearchers find CRISPR is capable of even more than we thought
Researchers studying key immune components of some CRISPR systems have announced the newest CARF effector they’ve discovered, which they coined Cat1 - it can deplete a metabolite essential for cellular function.
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NewsScientist awarded $500,000 Gruber Genetics Prize for pioneering discoveries in bacterial immune systems
The 2025 Gruber Genetics Prize is being awarded to geneticist and molecular biologist Rotem Sorek, Ph.D., of the Weizmann Institute of Science, for his discoveries in the immune system of bacteria.
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NewsScientists reveal key bacterial immune mechanism
Researchers have uncovered a pivotal mechanism by which bacteria defend themselves against viral infection. Cyclic dinucleotides (CDNs), synthesized during activation of the cyclic oligonucleotide-based anti-phage signaling system (CBASS) immune mechanism, trigger the filamentous assembly of phospholipase effectors, which execute the downstream immune response.
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NewsUltimate self-sacrifice: Bacteria activate unusual defense to evade viral attack
Scientists discover that the restriction modification system in some bacteria can kill the cell as a last resort if viruses try to thwart it. They trigger their own death using components of the very same systems that the phages were trying to inhibit.
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NewsBacteria use ancient war trick to outsmart viruses – and it could help us fight superbugs
Scientists have discovered a new type of immune defense in E. coli bacteria that turns viral infection machinery against the virus itself. They’ve named it Kongming after the Chinese military strategist who famously used enemy weapons to defeat his foes.
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NewsBacteria’s mysterious viruses can fan flames of antibiotic damage, according to new model
Researchers built a model that allows them to diminish phage communities from a mouse gut microbiome — and then bring them back — without affecting the bacteria. A test run found evidence that phages may increase gut bacteria’s sensitivity to antibiotics.
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NewsOpen benchmarking of CycloneSeq™ for complete bacterial genomes
Benchmark data and analysis of new CycloneSEQ using novel nanopore sequencing technology demonstrates the ability to sequence complete bacterial genomes.
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NewsThe very first structural images of a tuberculosis-fighting virus
Scientists have used advanced imaging techniques to provide a detailed look at how a tiny virus, known as a phage, invades Mycobacteria. The research could pave the way toward phage-based treatments for antibiotic-resistant mycobacteria.
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NewsResearchers release phage images with unprecedented detail
Researchers have produced the most detailed image to date of a bacteriophage, that has allowed them to see for the first time the structural makeup of the part of the phage that directly attaches to its target Mycobacterium cell.