All Clinical & Diagnostics articles
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NewsResearchers harness the microbiome to prevent deadly bloodstream infections
Researchers have pioneered a new approach to preventing dangerous bloodstream infections in patients receiving donor stem cell transplants for blood cancers. The first-of-its-kind therapy delivers 16 carefully selected beneficial bacteria designed to restore the microbiome and fight harmful pathogens.
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NewsCan the microbiome really change medicine? Scientists confront the evidence gap
At Targeting Microbiota 2026 in Málaga, international scientists will explore how microbiome discoveries can move beyond laboratory research toward evidence-based clinical applications.
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OpinionShigella: A phenotypic genus in a genomic era
In an era where evolutionary relationships can be resolved down to the single-nucleotide level, Shigella stands out as a relic of phenotype-based classification: a label built on lost traits rather than shared ancestry. Yet the genus persists, defended by appeals to clinical utility, says Georgina Donovan.
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NewsDistant climate patterns may offer early warning of Ebola outbreaks
Ebola outbreaks may leave a climatic trail months before they emerge. By analysing nearly five decades of outbreak data alongside large-scale climate oscillations, researchers identified distant weather patterns that could help flag periods and regions where Ebola risk may be increasing.
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NewsGut microbiome may help explain why sleep improvement varies after hydrogen supplementation
Hiroshima University researchers investigated the effects of hydrogen supplementation on sleep quality in healthy human volunteers. While hydrogen supplementation had no significant effect compared to a placebo, individuals in the hydrogen-supplementation group reporting better sleep quality were discovered to have a lower abundance of hydrogen producing bacteria in their gut microbiome.
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NewsHow clinicians can manage recurrent catheter bloodstream infections
Long-term intravenous catheters can be essential for treatment, but they also create a persistent risk of serious bloodstream infections. A new clinical review outlines how doctors can diagnose, treat and prevent recurrent infections while preserving vital vascular access whenever it is safe to do so.
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NewsU-M-led consortium to receive up to $52 million in NIH funding to study why viral respiratory infections affect children differently
A Michigan Medicine-led research consortium has secured approval for up to $52 million in federal funding to launch a multicenter study examining why some young children recover fully from viral lower respiratory tract infections while others develop severe illness or lasting problems such as asthma.
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NewsPlasmonic coating on bacterial surfaces paves the way for rapid sepsis diagnosis
Researchers have developed a label-free surface-enhanced Raman scattering (SERS) analysis technology that rapidly detects extremely low concentrations of viable bacteria by directly growing plasmonic metal nanostructures on and around bacterial cells.
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NewsHantavirus and the mouth: Review maps early oral warning signs, salivary clues, and precautions for dental teams
A review brings together the virology, epidemiology, clinical features, diagnosis, and treatment of human hantavirus infection and examines what each means for the mouth and for dental care.
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NewsImmune protein may fight viruses while limiting harmful inflammation
A naturally occurring immune protein may help the body fight viruses without triggering the damaging inflammation that can make infections worse. New research suggests interferon lambda can strengthen antiviral defences while keeping inflammatory responses under tighter control.
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NewsOne-step rapid syphilis test detects infection earlier, researchers report
A new rapid test detects lower levels of the two types of antibodies the body makes to fight syphilis bacteria and respond to disease-related cell damage, potentially leading to earlier interventions and fewer appointments for patients.
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FeaturesFaster results, harder decisions: interpreting syndromic panels in microbiological clinical practice
Every generation in diagnostic microbiology has tried to answer the same questions more quickly. Is an infection present? What is causing it? What should happen next? What has changed dramatically is how rapidly, and how broadly, laboratories can now search for answers to these questions.
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NewsResearchers engineer more sensitive CRISPR tool for virus detection
Researchers have engineered a more sensitive version of the RNA-targeting CRISPR enzyme Cas13a, improving its detection performance by 100-fold without sacrificing stability. The tool could support faster and more adaptable tests for HIV and a wide range of other RNA viruses.
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NewsPL-5 spray improves healing in infected burn wounds, phase IIIb trial finds
A late-stage clinical trial found that a topical spray called peceleganan (PL-5) helped adults with mild infected burn wounds heal better than placebo. It enrolled 348 adults and compared the spray with a placebo. The study tested once-daily treatment for 14 days and tracked wound closure, bacterial clearance, and safety.
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NewsWhat makes hantaviruses jump from rodents to humans?
Why do some hantaviruses jump from rodents to humans while others remain largely confined to wildlife? A new study will combine viral genetics, climate data and wildlife ecology to uncover the conditions that drive spillover and help identify where future outbreaks are most likely to emerge.
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NewsResearchers publish clinical data for rapid diagnostic urine test to detect invasive aspergillosis
Through long-standing research, which has been supported by the National Institutes of Health, investigators at Johns Hopkins Medicine have advanced insights into ways to better detect invasive aspergillosis (IA). Caused by mold, the infection is uncommon in the general population but can create significant health risks for people with underlying ...
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NewsNew study raises questions about antifungal treatments during pregnancy
A study suggests that common antifungal medicines used during pregnancy may be associated with changes in foetal hormone production. However, the researchers cannot yet say whether the differences observed have consequences for the children later in life.
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NewsResearchers built a low-cost system that knows when coughing is on the rise
What if a room could tell when coughing is on the rise without cameras or identifying anyone? Researchers have developed a low-cost sensor system that uses microphones, AI and lightweight computing to count coughs and distinguish between different coughers, potentially helping hospitals spot increases in respiratory illness earlier.
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NewsOncolytic viruses and CAR cells team up against solid tumors
Oncolytic viruses and CAR-T or CAR-NK cells could be engineered together to overcome some of the biggest barriers in solid tumor treatment. A new review outlines how these therapies may be combined into programmable systems that improve tumor targeting, immune-cell infiltration and sustained antitumor activity.
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NewsRapid genomic test identifies fungal bloodstream infections
Researchers have developed a rapid genomic method that can identify fungal bloodstream infections at the species level in about seven hours. By combining host DNA depletion, whole-genome amplification and real-time nanopore sequencing, the approach could help clinicians select appropriate antifungal treatment much earlier.