All Clinical & Diagnostics articles
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NewsHospital expands newborn screening to identify virus that can lead to hearing loss and developmental delays
Researchers have developed a new screening program for congenital cytomegalovirus, the most common infection passed from mothers to babies during pregnancy. While many babies with congenital cytomegalovirus have no obvious symptoms, some can develop hearing loss, developmental delays or other medical complications as they grow.
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NewsGut microbiome development may help predict type 1 diabetes in children at high risk
A new prospective study found that children at high genetic risk of type 1 diabetes whose gut microbiome development plateaued early had about three times the risk of developing the disease compared with children whose microbiomes continued to mature.
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NewsNew sepsis guidelines seek to reduce infection’s deadly toll
Experts have developed important new guidelines to improve care for patients who develop sepsis, a dangerous full-body infection that kills at least 350,000 Americans every year.
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NewsNew test could dramatically speed diagnosis of hard-to-detect lung infections
Nontuberculous mycobacteria can cause chronic, tuberculosis-like lung infections. Researchers have developed a new diagnostic platform that can identify the precise species of bacteria causing a patient’s infection in just a few hours — a dramatic improvement over the current standard, which can take four to six weeks.
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NewsGut microbiome features predict devastating disease affecting preemies
In a discovery that challenges long-standing assumptions about necrotizing enterocolitis, researchers have identified previously unknown predictors for the disease. They found that bacteria-infecting viruses and bacterial antibiotic resistance genes in the gut microbiomes of babies are additional harbingers of necrotizing enterocolitis.
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NewsResearchers discover how Epstein-Barr Virus triggers multiple sclerosis attacks
In a study of blood samples from more than 100 participants with MS, researchers detected increased EBV lytic activity in immune cells up to three months before MS relapse and discovered that these cells also showed elevated expression of genes linked to MS risk.
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NewsLab tackles antibiotic resistance across multiple fronts in new trio of studies
To defeat multidrug-resistant superbugs, bacterial defenses must be confronted wherever they may emerge, from basic genetic mutations in a laboratory, to complex real-world transmission in hospital rooms. A new trio of studies demonstrates how an integrated approach might yet expose and overcome these diverse survival mechanisms.
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NewsFecal microbial signatures show promise for colorectal and pancreatic cancer assessment
Gastrointestinal and pancreatobiliary cancers can be difficult to detect early, creating a need for practical, noninvasive approaches for early detection and risk assessment. The gut microbiome has emerged as a potential source of cancer biomarkers, offering practical opportunities for noninvasive testing, as microbial changes can be assessed in fecal samples. ...
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NewsFewer infections, more azithromycin use seen among emergency c-section patients following publication of clinical trial results
Researchers investigated if azithromycin use and postpartum infection rates changed after publication of trial evidence in 2016 among US pregnant women who underwent an unscheduled cesarean delivery.
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NewsThe usefulness of labelled white blood cells in diagnosing necrotizing external otitis
Using radiopharmaceutical technology, researchers can reliably and conveniently diagnose and monitor necrotizing external otitis, a rare disease of the skull base.
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NewsMultiplexed saliva-based immunodiagnostics for assessing anti-flavivirus immunity
Researchers have unveiled a saliva-based assay that rapidly, accurately, and noninvasively assesses flavivirus immunity by measuring multiple antibody classes in saliva.
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NewsGut, airway and tumor microbes emerge as promising predictors of immunotherapy response in lung cancer
A comprehensive review systematically evaluates the microbiome’s role in lung cancer immunotherapy. Authors synthesized evidence covering microbial communities in the oral cavity, airways, lung tumors and gut, and their connections to treatment efficacy and immune‑related adverse events.
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NewsExpert consensus outlines 12 recommendations to prevent secondary mucormycosis after respiratory viral infections
The recommendations focus on defined high-risk patients, early viral testing and treatment, hospital infection control, and practical measures for resource-limited settings.
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NewsFaster diagnostics, deeper insights: Researchers strengthen response to Ebola outbreaks
Two studies provide important insights into the challenges of responding to outbreaks - one demonstrates how diagnostic tests can be evaluated rapidly during an outbreak; the other investigates the biological properties of the 2026 BDBV strain and whether an existing Ebola vaccine could offer cross-protection.
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NewsMeningitis, hangover or freshers’ flu? Don’t dismiss serious symptoms
Students heading into freshers’ week are being warned not to assume a headache, vomiting or feeling wiped out is simply the result of a heavy night or the dreaded “freshers’ flu”. 246,089 doses of the MenB vaccine were administered to young people in England between 20 July and 31 August.
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NewsDifference in clinical characteristics and outcomes between hospital-acquired and community-acquired pleural infection
A critical aspect of managing pleural infection is understanding differences between hospital-acquired and community-acquired forms, as these two entities differ fundamentally in etiology, microbiology, antimicrobial resistance patterns, and patient populations.
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NewsVaricella zoster virus can cause serious disease beyond chickenpox and shingles
New research is shedding light on the surprisingly broad range of neurological and systemic diseases that can be caused by varicella zoster virus (VZV), the virus that causes chickenpox and shingles.
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NewsThe push to understand and treat HPV
Karl Munger is helping to lead an effort at Tufts University and Tufts Medicine that brings research scientists together with clinicians to save lives through improved HPV care and research.
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NewsAncient Dujiangyan water wisdom inspires AI microfluidic chip to spot hidden sub-resistant bacteria
To pinpoint hidden populations of bacteria, researchers have developed a deep learning-based microfluidic rapid phenotypic AST system, named DP-AST, inspired by the “six-four water diversion” principle of the ancient Dujiangyan irrigation system in China.
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NewsScientists uncover shared biology behind profound fatigue in five major illnesses
New research identifies a shared biological secret that helps explain chronic exhaustion in conditions including long Covid and PTSD.