All Clinical & Diagnostics articles
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NewsA ‘one-pot’ assay of or rapid portable identification of genotypes I and II African swine fever viruses
Researchers in search of an African swine fever virus genotyping method developed an isothermal ‘one-pot’ CRISPR-Cas12i3/Cas13d-based assay, designated OBServe.v2, to detect two amplified targets from multiplex recombinase polymerase amplification (RPA) in a single tube.
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NewsCan an electronic nose detect indoor mold?
Researchers have developed an electronic nose that can reliably sense and identify mold, which causes various health issues for humans and animals, as well as damage to homes and other buildings and structures.
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NewsNew method accelerates resistance testing in urinary tract infections
Researchers have developed two methods that allow urine samples to be tested directly for antibiotic susceptibility. Because the procedures do not require standardized bacterial suspensions, the time to result is reduced by up to 24 hours compared to conventional testing.
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NewsWho is more likely to get long COVID?
Scientists have identified the key genetic drivers behind long COVID, revealing why some people continue to experience debilitating symptoms long after their initial infection.
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NewsNew 15-minute hepatitis C test paves the way for same-day treatment
Scientists have developed the fastest test yet for diagnosing hepatitis C virus (HCV). The highly accurate diagnostic delivers results to patients in just 15 minutes - crucial for kickstarting patients’ treatment before they leave their appointment.
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NewsCARB-X to support investigation of Exhalon’s breath-based lower respiratory tract infection testing platform
CARB-X has awarded Exhalon US$1M in seed funding to evaluate whether exhaled breath can be used as a non-invasive sample type to aid in the rapid and accurate diagnosis of lower-respiratory tract infections (LRTIs).
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NewsInside the gut: What our poo could tell us about our diet, gut microbes and health
Researchers have found that molecules in stool samples can accurately reflect what people eat and how their gut microbiome responds, offering a potential new tool to study nutrition and its impact on health.
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NewsSingle-cell movies reveal how host physiology sets phage success - and how to time therapies
A new study outlines how an innovative imaging platform can be used to help uncover the reasons why phages succeed or fail when used to target bacterial infections.
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NewsNew test distinguishes vaccine-induced false positives from active HIV infection
A new device correctly identified those with active HIV-1 infection 95% of the time and those without active infection but with vaccine-induced molecules that could trigger a false positive, 98% of the time.
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NewsBridging controversy: New international guidelines redefine diagnosis and treatment of fungal eye infections
A global expert panel from the Asia-Pacific region has now issued 20 consensus statements providing comprehensive, evidence-based guidance for the diagnosis and management of a sight-threatening condition - fungal endophthalmitis.
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NewsPoint-of-care rapid tests can improve screening for latent tuberculosis
A new test shows promising results for detecting latent tuberculosis infection in resource-limited settings. Latent tuberculosis is often diagnosed using a laboratory test called QuantiFERON-TB Gold Plus - this was compared with another test, TB-Feron.
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CareersSummer studentship: Oliver probes AMR in neonatal sepsis - and use of novel bacterial screening methods.
Oliver Spiller-Boulter, from Cardiff, reports back on his AMI-sponsored summer studentship which examined antimicrobial resistance (AMR) in neonatal sepsis and the use of novel bacterial screening methods.
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NewsCorticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis found that adjunct corticosteroids probably reduce short-term mortality in cases of severe pneumonia and acute respiratory distress syndrome and may reduce secondary shock in severe pneumonia.
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NewsLong-term HIV control: Could this combination therapy be the key?
A new study shows it may be possible to control HIV without long-term antiviral treatment — an advance that points the way toward a possible cure for a disease that affects 40 million people around the world.
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NewsNew prevention tools and investment in services essential in the fight against AIDS
On World AIDS Day, the World Health Organization (WHO) calls on governments and partners to rapidly expand access to new WHO-approved tools including lenacapavir (LEN) to drive down infections and counter disruption to essential health services caused by cuts to foreign aid.
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NewsNew guideline on pre-exposure and postexposure HIV prevention
Multiple pre-exposure (PrEP) and postexposure (PEP) treatments are now available to prevent HIV infection. An updated Canadian guideline contains 31 recommendations and 10 good practice statements to help clinicians and other health care professionals offer these options to patients.
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NewsBird flu viruses are resistant to fever, making them a major threat to humans
Bird flu viruses are a particular threat to humans because they can replicate at temperatures higher than a typical fever, one of the body’s ways of stopping viruses in their tracks, according to new research.
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NewsFractional-dose vaccines can save millions during shortages
New research shows that using smaller, fractional doses of vaccines can significantly reduce infections during epidemics, especially when vaccine supply, delivery, or administration capacity is limited.
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NewsExperimental mRNA therapy shows potential to combat antibiotic-resistant infections
Researchers have reported early success with a novel mRNA-based therapy designed to combat antibiotic-resistant bacteria. In preclinical studies, the therapy slowed bacterial growth, strengthened immune cell activity, and reduced lung tissue damage in models of multidrug-resistant pneumonia.
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NewsHospital bug jumps from lungs to gut, raising sepsis risk
A hospital-acquired bacterium that causes serious infections can move from the lungs to the gut inside the same patient, raising the risk of life-threatening sepsis, new research reveals.