All Antimicrobials articles
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NewsAMI welcomes new member to its Board of Trustees
Applied Microbiology International has welcomed Professor Les Baillie as the latest member of its Board of Trustees. We also bid a fond farewell and thank you to Professor Diane Purchase who is leaving the Board.
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NewsResearchers discover highly potent compound that blocks Ebola virus entry
A research team has discovered a highly potent small molecule that blocks Ebola virus entry by stabilizing the virus’s entry protein and provides strong protection when given orally in a preclinical model. It is more than 100 times more potent than previously reported Ebola entry inhibitors.
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NewsC. diff coordinates threat response to survive in gut
Researchers have discovered a unique system C. diff uses to simultaneously sense and respond to two different threats: host-mediated nutrient deprivation and a microbiota-produced antibiotic compound, suggesting new therapeutic options for preventing and treating C. diff infections.
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NewsVaccine protects against multiple fungal infections without hurting the gut
A vaccine created to battle multiple life-threatening fungal infections is successful in achieving protective immunity in pre-clinical animal models while also maintaining the biodiversity of the gut microbiome, according to a new study.
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NewsKazakh researchers ID antiviral and anti-inflammatory compounds in native medicinal plants
Researchers have identified biologically active compounds with antiviral, antimicrobial, and anti-inflammatory effects in several plant species native to Kazakhstan, providing new chemical and experimental data on medicinal flora from Central Asia.
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NewsBlueberry’s waxy shield reveals clues to gray mold resistance
Botrytis cinerea is a broad-host-range necrotrophic fungus that causes gray mold in more than 1,000 plant species. In blueberry, it can damage flowers in the field and later emerge as fruit rot after harvest, reducing shelf life, shipment quality and market value. The disease is especially challenging because latent infections ...
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NewsA fourth T6SS in clinical Pseudomonas aeruginosa deploys the pore-forming effector TseMt
The hospital-associated pathogen Pseudomonas aeruginosa has type VI secretion systems (T6SSs). Most reference strains encode three T6SSs, but comparative genomics has identified an additional H4-T6SS in a subset of clinical isolates.
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NewsWild tomatillos coat fruits with sticky chemical arsenal, study finds
For decades, research on plant chemical defenses has focused on glandular trichomes—the tiny hair‑like structures on leaves and stems that produce and secrete protective compounds. Acyl sugars, a class of specialized metabolites widespread in the nightshade family (Solanaceae), are known to deter insects and fungal pathogens when produced in leaf ...
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NewsAnti-influenza therapies that target the host
Researchers suggest that nucleolin-binding drugs are a promising avenue of research in the quest to overcome drug resistance and improve influenza management worldwide.
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NewsEmergence of Stutzerimonas nitrititolerans co-carrying carbapenem and tigecycline resistance from geese in China
Researchers have found strains of Stutzerimonas nitrititolerans with resistance to meropenem and reduced susceptibility to tigecycline in geese feces in Yangzhou, China.
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NewsPomegranate emerges as a promising natural phytobiotic for veterinary medicine
Researchers have identified a broad range of biological properties in pomegranate with potential for use in medical applications, including antimicrobial, antiparasitic, antioxidant, immunomodulatory, antidiabetic, anti-inflammatory and wound-healing effects.
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NewsNew discovery could help scientists fight deadly fungal infections
Researchers have discovered that the bacterial antibiotic ‘gladiolin’ can disarm Candida albicans, one of the leading causes of life-threatening fungal infections, opening new avenues for developing life-saving treatments.
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NewsDevelopment of dual-action compounds to fight cancer and infections
Researchers have developed new hybrid compounds that simultaneously reduce the viability of aggressive cancer cells and inhibit the growth of certain bacteria and fungi.
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News‘Known’ TB gene springs to action under stress, with an unexpected biological role
New research has discovered that one of TB’s supposedly “known” genes has a completely unexpected biological role, with far-reaching implications.
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NewsPreventive TB treatment for individuals with HIV shown to be effective in real-world settings
A new study has evaluated the real-world impact of TB preventive treatment in six countries with high TB and HIV rates and highlights the importance of preventive treatment in reducing deaths caused by a curable disease.
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FeaturesA century of colicin: how a problem became the cure
Since the dawn of time, bacteria have evolved sophisticated ways to wage war against one another. Among the most fascinating of these natural weapons are colicins — protein toxins produced by certain strains of Escherichia coli (E. coli) to eliminate competing bacteria. This article examines how these remarkable molecules were ...
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NewsResearch sheds more light on the antimicrobial properties of mānuka honey
New research has shown that a variety of compounds is responsible for the antimicrobial action of mānuka honey, not just the sugar content and methylglyoxal (MGO) alone, as previously thought.
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NewsLong-acting therapies continue to gain momentum in HIV, says GlobalData
The next phase of competition in the HIV market will be defined not only by achieving viral suppression, but improving treatment adherence, reducing medication burden and delivering more convenient treatment options, says a new analysis.
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NewsTriple-dose regimen may permanently clear HIV in infected newborns
New research suggests a one-time regimen of therapies given to newborns within three days of birth could permanently clear HIV infection.
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NewsNew viral marker strategies improve prediction of functional cure in chronic hepatitis B
Researchers identify how combining classical and emerging viral biomarkers can better predict functional cure and guide individualized hepatitis B treatment.