All Antimicrobials articles
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NewsStudy reveals how bacteria assemble their envelope
Researchers have discovered a key process for how the outer membrane of gram-negative bacteria attaches to the cell wall, advancing the understanding of how these bacteria frequently manifest resistance to antibiotics.
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NewsScientists probe antiviral molecules in bacteria that target bacteriophages
Researchers have examined the antiviral molecule daunorubicin, produced by Streptomycetes, and decoded its mode of operation against viruses. They now describe this mechanism, which primarily targets a specific group of viruses – namely bacteriophages.
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NewsBiomaterial made from jackfruit latex is a promising treatment for periodontitis
Researchers have developed a biomaterial containing jackfruit latex, pomegranate peel extract, and simvastatin that shows promising efficacy in treating periodontitis. This chronic inflammatory disease of infectious origin leads to the progressive destruction of the tissues supporting the teeth, resulting in bone resorption and loss of attachment.
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NewsHealth researchers call for support to develop pandemic prevention
The Vanderbilt Center for Antibody Therapeutics has received large-scale government grants and contracts to fund the discovery of human antiviral antibodies. The problem is the next step — finding corporate partners to develop the antibodies through human testing.
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NewsExperts convened by WHO advise on candidate treatments and vaccines for Ebola disease caused by Bundibugyo virus
In response to the current outbreak of Ebola disease caused by Bundibugyo virus, WHO convened several of its expert and advisory groups to assess potential vaccines and therapeutics for both prevention and treatment of Bundibugyo virus disease (BVD).
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NewsScientists develop an antifungal aqueous suspension to prevent fungal infections in crops and fruit
Researchers have developed an antifungal aqueous suspension for the prevention of fungal infections in crops and fruit during the pre- and post-harvest stages. The new formulation is aimed at the biotechnology and agricultural sectors.
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NewsScientists identify nearly two dozen antiviral compounds that could treat Ebola virus
Recent advances in artificial intelligence have enabled scientists to identify nearly two dozen antiviral compounds that could potentially treat a rare species of Ebola virus (Bundibugyo virus) currently affecting the Democratic Republic of Congo.
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NewsResearchers investigate soil microbes from around the world for new antibacterial drugs
A team of researchers is looking to nature to find microbes that can be used to create new antibiotics to treat the growing threat of drug-resistant bacteria. They will screen soil microbes from around the world to hunt for sources of new antibacterial drugs.
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NewsPatent targets viruses with a breakthrough from linseed oil
A common vegetable oil may hold the key to fighting some of the world’s most dangerous viruses. Scientists have patented a linseed oil polyol-derived compound shown to inhibit viral infections including HIV and SARS-CoV-2 as well as bacterial infections causing strep and staph.
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NewsA common disinfectant could affect how well your liver works
Common household cleaners and pharmaceutical products contain benzalkonium chlorides (BACs), a type of disinfectant. A new study shows that exposure to these compounds caused changes in gut microbiome composition in mice, as well as the genes that encode for liver enzymes that metabolize drugs.
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NewsWine’s leftovers could help wean chicken farms off antibiotics
Every year, millions of gallons of wine are pressed, leaving behind a mountain of pulpy residue that wineries struggle to dispose of. Now, researchers say this overlooked byproduct could serve as a replacement for the antibiotics routinely added to chicken feed.
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NewsThe hunt for red: Chromatin-mediated upregulation of Monascus pigments in Talaromyces purpurogenus OUCMDZ-019 via disruption of Ash2
The industrial application of Monascus pigments has been hindered by three key bottlenecks: unstable yield, poor environmental stability, and the risk of contamination by citrinin. Researchers adopted an epigenetic derepression strategy to unlock the hidden biosynthetic potential of MPs in Talaromyces purpurogenus OUCMDZ-019.
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NewsPenn researchers create AI tool to speed antibiotic discovery
Researchers have developed a novel, AI-powered method for turning promising but imperfect antibiotic candidates into more potent ones. ApexGO starts with a small number of imperfect candidates and improves them step by step, using a predictive algorithm to evaluate each modification and guide the next.
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NewsStudy reveals common mutation linked to autoimmune diseases may protect people from viral infections
New research shows a “risk gene” linked to higher odds of developing autoimmune diseases such as diabetes or lupus may also provide a survival advantage fighting viral infections like coronavirus. The gene PTPN22 carries a mutation, 1858C>T (R620W), found in roughly one in 10 people in North America.
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NewsCRISPR system inhibits hepatitis E virus
Researchers have developed a novel antiviral concept - using the CRISPR/Cas13 system, they were able to specifically suppress the replication of the hepatitis E virus in human cells.
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NewsFungi utilize ancient antimicrobial proteins to attack hosts and their microbiomes
An international research team has discovered the surprising evolutionary origin of fungal effector proteins: molecules that pathogens use today to infect their hosts appear to have evolved from ancient antimicrobial proteins.
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NewsAncient, insect-targeting bacterial toxin may have implications for human health, agriculture, and drug discovery
Scientists have identified and characterized a new class of Streptomyces-produced toxins that are very distantly related to the deadly toxin that causes diphtheria, a serious and contagious infection, in humans.
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NewsNew study suggests seasonal flu vaccines may reduce severity of H5N1 bird flu infections
Researchers have found that seasonal influenza vaccines in routine global use may significantly reduce the risk of death from H5N1 infection. The findings that readily available tools may offer protection while the world races to develop more targeted solutions.
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NewsEight-year results from two randomized phase 3 trials of tenofovir alafenamide for chronic hepatitis B virus infection in China
Tenofovir alafenamide (TAF) has demonstrated comparable efficacy to tenofovir disoproxil fumarate (TDF), with improved renal and bone safety, in Chinese participants with chronic hepatitis B enrolled in two Phase 3 trials.
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NewsScientists catch a fungal enzyme open for business
A new study shows that caspofungin, a widely used antifungal drug, works only when its target enzyme is active, pointing the way toward designing better treatments.