All Gut Microbiome articles
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NewsGene-regulatory pathway helps T cells tolerate gut bacteria and prevent inflammation
The immune system somehow tolerates trillions of gut bacteria without constantly attacking them. Researchers have now identified a gene-regulatory pathway that helps regulatory T cells maintain this peace, with defects in the pathway triggering severe inflammation and autoimmunity in mice.
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NewsScientists propose national microbiome plan to prevent chronic disease
Leading microbiome researchers are calling for a global ‘moonshot’ to determine how the microbes living in and on our bodies contribute to chronic disease. The proposed agenda would combine long-term human studies, clinical trials, global research standards and public education to move the field from promising associations towards proven causes and treatments.
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NewsGut microbiome may help explain why sleep improvement varies after hydrogen supplementation
Hiroshima University researchers investigated the effects of hydrogen supplementation on sleep quality in healthy human volunteers. While hydrogen supplementation had no significant effect compared to a placebo, individuals in the hydrogen-supplementation group reporting better sleep quality were discovered to have a lower abundance of hydrogen producing bacteria in their gut microbiome.
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NewsTargeting the gut-liver axis: New review explores microbial modulation to enhance immunotherapy in hepatocellular carcinoma
A review examines how gut microbiota and their metabolites reshape the hepatic immune microenvironment through the gut–liver axis, influence immune checkpoint inhibitor efficacy, and explore emerging combination strategies, including fecal microbiota transplantation, probiotics, engineered bacteria, and metabolite-based interventions.
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NewsCan better gut health help patients with ovarian cancer tolerate chemotherapy?
A new clinical trial is testing whether probiotics can help patients with ovarian cancer better tolerate chemotherapy. The trial will look at whether probiotics can help reduce treatment side effects and improve quality of life. Researchers will also study how changes in the gut microbiome may be linked to treatment response.
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NewsGut-inspired biobattery uses bacteria to generate electricity
The tiny finger-like structures lining our small intestine have inspired a new design for bacteria-powered batteries. By mimicking intestinal villi, researchers created a bioelectrode with more surface area and better nutrient flow, allowing bacteria to generate stable electricity for hours.
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NewsAntibiotic use from childhood linked to higher odds of IBS in young adulthood
Antibiotic use from childhood through early adulthood was associated with higher odds of irritable bowel syndrome (IBS) at age 24, with the odds increasing as the number of antibiotic prescriptions rose, according to a new study.
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NewsGut microbes don’t just train the immune system—they keep it in shape
Immune maturation has long been viewed as a developmental milestone tied to weaning, when pups are first exposed to a flood of dietary antigens and colonizing microbes. A study now suggests that in mice, the immune competence established after weaning is not self-sustaining—it must be continuously maintained by signals from the commensal microbiota.
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NewsHow E. coli eavesdrops and senses Bifidobacterium
Gut bacteria may be quietly listening in on one another’s metabolism. Researchers have discovered that E. coli can detect chemical signals released by Bifidobacterium, allowing it to sense what nearby bacteria are doing and adjust its own metabolism in response.
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NewsStudy finds Helicobacter pylori exposure may be associated with more than one in five colorectal cancer cases worldwide
An international collaborative research study has found that exposure to Helicobacter pylori, a bacterium known to cause stomach ulcers and gastric cancer, may be associated with approximately 22% of colorectal cancer cases globally.
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NewsResearchers explore link between gut, brain health for people with HIV
Oregon Health & Science University researchers have secured a $5.8 million, five-year federal award to investigate whether damage to the gastrointestinal tract contributes to neuroinflammation in people living with HIV — raising the potential for new treatments to preserve brain function in people with HIV and older adults.
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NewsA natural compound takes aim at C. difficile while sparing the gut microbiome
Researchers identify argyrin B, a promising natural compound that targets the bacterium behind dangerous intestinal infections while leaving beneficial gut microbes largely unharmed. The discovery could pave the way for new treatments with fewer relapses and side effects.
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NewsBeetles build with a yellow pigment gene
More than 80 years ago scientists discovered that differences in yellow pigmentation were critical to courtship success and failure for fruit flies. New research has added a deeper perspective to the study of Yellow, showing how in tortoise beetles this protein has been co-opted as a building material to house symbiotic bacteria.
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NewsGut microbes across continents trace ancient human migration
A new study has attempted to answer the question of whether homo sapiens hosted a characteristic and diverse microbiome going back millennia. Gaining insight into which, if any, long-term residents of the microbiome co-evolved with humans could point to ways to investigate how the loss of microbial diversity through industrialization impacts human biology.
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NewsStudy may explain why IBD patients react to foods they once tolerated
A new study finds that gut inflammation can change the way gut bacteria break down food — possibly triggering immune reactions to foods that were previously fine to eat. The findings may help explain why so many people with inflammatory bowel disease (IBD) react badly to foods like dairy or gluten, even in remission.
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NewsGut bacteria shape how fiber works
Eating more fiber does not necessarily mean the same thing for every gut microbiome. New research shows that plant-based carbohydrates can favor Segatella copri only when certain other bacteria are already present, revealing how strongly diet depends on the microbial community it enters.
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NewsModel traces C. diff spread in hospital oncology units
In a new study, researchers modeled the transmission of Clostridioides difficile infections among patients in hospital cancer units. They found that most new infections were introduced by patients who were infected but not symptomatic at the time of admission, rather than by patients who were infected and symptomatic.
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NewsHow gut bacteria can shape the brain’s response to stroke
How much damage a stroke causes in the brain depends strongly on how quickly blood flow can be restored. The patient’s own immune response that follows the stroke also plays an important role. Researchers have identified a specific bacterial signal that shapes this immune response and influences stroke outcome.
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NewsSugar amplifies damage done to gut health by antibiotics
Eating sweets while taking antibiotics may worsen the harm done by the drugs to the normal community of bacteria in the gut, a new study has found. The study of hospitalized cancer patients found an additional 21% reduction in the variety of helpful bacterial species present for every 100 grams of sugar consumed in the 48 hours before treatment.
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NewsBlueberries modify gut microbiome in older adults with mild depression
A new pilot study has found that older, sedentary adults who consumed blueberries daily showed a greater, more consistent reduction in depressive symptoms, paired with minor changes in markers of gut microbial enzymes.